Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial
Gestores bibliográficos
Compartir
item.contributor.advisor
ORCID:
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Ltd.
item.page.isbn
item.page.issn
item.page.issne
item.page.doiurl
item.page.extent
item.page.accessRights
item.page.other
item.page.references
Abstract
Background
Systolic blood pressure of more than 185 mm Hg is a contraindication to thrombolytic treatment with intravenous alteplase in patients with acute ischaemic stroke, but the target systolic b...
Description
item.page.coverage.spatial
item.page.sponsorship
Citation
Craig S Anderson, Yining Huang, Richard I Lindley, Xiaoying Chen, Hisatomi Arima, Guofang Chen, Qiang Li, Laurent Billot, Candice Delcourt, Philip M Bath, Joseph P Broderick, Andrew M Demchuk, Geoffrey A Donnan, Alice C Durham, Pablo M Lavados, Tsong-Hai Lee, Christopher Levi, Sheila O Martins, Veronica V Olavarria, Jeyaraj D Pandian, Mark W Parsons, Octavio M Pontes-Neto, Stefano Ricci, Shoichiro Sato, Vijay K Sharma, Federico Silva, Lili Song, Nguyen H Thang, Joanna M Wardlaw, Ji-Guang Wang, Xia Wang, Mark Woodward, John Chalmers, Thompson G Robinson, Craig S. Anderson, Yining Huang, Richard I. Lindley, Xiaoying Chen, Hisatomi Arima, Guofang Chen, Qiang Li, Laurent Billot, Candice Delcourt, Philip M. Bath, Joseph P. Broderick, Andrew M. Demchuk, Geoffrey A. Donnan, Alice C. Durham, Pablo M. Lavados, Tsong-Hai Lee, Christopher Levi, Sheila O. Martins, Veronica V. Olavarria, Jeyaraj D. Pandian, Mark W. Parsons, Octavio M. Pontes-Neto, Stefano Ricci, Shoichiro Sato, Vijay K. Sharma, Federico Silva, Lili Song, Nguyen H. Thang, Joanna M. Wardlaw, Ji-Guang Wang, Xia Wang, Mark Woodward, John Chalmers, Thompson G. Robinson, Jong S. Kim, Christian Stapf, R. John Simes, Graeme J. Hankey, Peter Sandercock, Marie-Germaine Bousser, K.S. Lawrence Wong, Anish Scaria, Yoichiro Hirakawa, Tom J. Moullaali, Cheryl Carcel, Penny Gordon, Sully X. Fuentes-Patarroyo, Dino Benito, Ruiqi Chen, Yongjun Cao, Amy Kunchok, Stephen Winters, Shelagh Coutts, Sohei Yoshimura, Shoujiang You, Jie Yang, Guojun Wu, Shihong Zhang, Lisa Manning, Amit Mistri, Victoria Haunton, Jatinder Minhas, Alejandra Malavera, Joyce Lim, Leibo Liu, Namrata N. Kumar, Nicole Tay, Kerry Jenson, Sarah Richtering, Sharon Tucker, Elizabeth Knight, Elizaveta Ivanova, Emma Thembani, Elizabeth Odgers, Elizabeth Sanders, Sabrina Small, Ruchita Vaghasiya, Manuela Armenis, Paul Donnelly, Merza A. Baig, Nick Blacklock, Bala Naidu, Helen Monaghan, Phillipa Smith, Parisa Glass, Xuejie Bai, Qiancheng Li, Pingping Zhu, Liang Kong, Ruihong He, He Zhao, Jiajie Lv, Haijing Jia, Zhen Xi, Yuhan Cong, Buliang Cui, Hua Deng, Ying Guo, Lingyu He, Ruolan Jia, Nan Li, Wei Li, Mengxiao Liu, Meng Zhang, Ziwei Xu, Ting Zhang, Yan Zhao, Philip Gregory, Yunjeong In, Su J. Kim, Jung E. Ahn, Sul H. Kim, Young L. Hong, Francisca González-McCawley, Magda C.O. Martins, Bernardita Portales, Ching-Yi Wang, Shan-Jen Ryu, Hardeep Aujla, Sue Lewin, Tracy Kumar, Sara Barrows, Ahtasam Ebraimo, Hong H. Uyen, Nguyen A. Giang, Le T.M. Linh, Le T.T. An, Do M. Phuong, Pham V.B. Ngoc, Nguyen M. Hang, Nguyen T.B. Tran, Ha T.T. Hien, Mai B. Yen, Ngo T.B. Tram, Tran T.T. Truc, Nguyen A. Hoa, Nguyen T.B. Thuan, Ha T.K. Oanh, Deepti Arora, Shweta J. Verma, M. Krause, M. Priglinger, S. Day, S. Jala, L. Davies, E. Ray, S. Celestino, L.Y. Law, T. Wijeratne, G. Ng, K. Nagao, G. Weiss, N. Titton, C. Batista, D. Zãn, L. Carbonera, K. Ferreira, R. Castro, R.K. Martins Filho, M. Carvalho, M. Libardi, G. Martins, D. Fagundes, G. Baron, A. Boehringer, J. Barbosa, R. Bazan, G. Braga, G. Luvizutto, P. Ribeiro, F. Winckler, C. Moro, A. Longo, R. Liberato, R. Barbosa, P. Magalhães, M. Portal, K. Martin, A. Souza, D. Cuervo, D. Perin, L. Marques, F. Oliveira, M. Battaglini, F. Lourenço, K. Ferreira, G. Silva, L. Duarte, M. Alves, J. Sousa, M. Uhehara, A. Brunser, E. Mazzón, M. Spencer, I. Acosta, A. Rojo, R. Rivas, C. Klapp, L. Carvallo, P. Carvallo, E. Mansilla, J. Flores, M. Alvarado, A. Herrera, C. Reyes, F. Jurado, G. Bustamante, L. Bravo, J.M. Matamala, R. Guerrero, S. Zhou, L. Ping, W. Liu, L. Liu, Y. Tian, H. Xu, J. Wang, L. Wang, Z. Zhen, L. Wang, J. Zhang, M. Yan, L. Wang, Q. Zhang, X. Tao, C. Liu, J. Shi, X. Zhang, L. Tai, L. Xu, H. Lu, H. Nie, X. Li, J. Zhou, Y. Liu, P. Gong, Y. Tian, H. Zhao, J. Zhang, R. Li, X. Wang, Q. Chen, Y. Li, L. Wu, J. Zhang, L. Jia, X. Guo, X. Li, G. Chen, B. Lin, W. Zhu, K. Yang, J. Zhang, Z. Zhang, C. Xie, D. Wu, Z. Zhang, X. Li, Y. Wang, D. Liu, Z. Liu, L. Liang, Q. Cao, X. Zhang, J. Xia, X. Li, Y. Weng, J. Li, T. Xu, D. Geng, X. Yan, D. Wang, N. Zhao, J. Li, D. Wang, Z. Tang, L. Wang, W. Yin, S. Wang, D. Wang, W. Huang, Y. Yang, A. Song, Y. Hao, A. Zhang, B. Qiao, J. Yang, H. Yan, X. Wei, Z. Tao, H. Liu, Y. Lv, H. Yang, L. Han, X. Mao, L. Ge, Y. Zhang, S. He, Q. Zhang, H. Zhao, J. Jiang, M. Yan, D. Liu, W. Wu, H. Wang, Y. Wang, L. Yang, Y. Tang, H. Sun, F. Li, G. Li, Y. Sun, H. Zhang, Y. Wu, L. Huang, C. Geng, Z. Jin, J. Zhu, F. Zhang, Y. Zhang, Z. Zhang, R. Zheng, H. Shen, F. Liu, C. Chen, G. Li, S. Chen, L. Zhou, B. Hu, Z. Zou, J. Liu, X. Zhang, X. Chang, D. Wang, S. Zhang, Q. Huang, X. Liu, S. Liu, W. He, J. Feng, L. Li, X. Chen, X. Zhuang, Y. Liu, W. Zheng, Y. Lai, Y. Zhou, H. Duan, Q. Cao, Q. Yang, J. Du, Q Lin, E. Xu, L. Zhan, L. Yang, Q. Huang, J. Wu, X. Feng, C. Wei, J. He, B. Wang, X. Liu, W Li, P Chen, F Guo, H Dai, M Dai, X. Zeng, D. Wang, B. Chen, F. Long, Q. Su, Y. Wang, B. Bao, T. Wu, X. Wu, Y. Shao, H. Nie, X. Zhang, S. Li, Y. Xu, J.A. Castellanos, M. Muñoz-Collazos, E. Solano, W.H.T. Leung, S. Sureshbabu, S.N. Sharma, S. George, S. Shekhar, S. Singla, L. Saini, - Sunita, M. Kate, R. Sarvotham, A.G. William, A. Deepak, M. BK, R. Benny, V. Bolegave, M. Basle, S. Gore, P. George, S. Kumaravelu, S. Rahamath, P.G. Raj, A.R. Devi, A. Sharma, J. Prajapati, M. Parmar, D. Patel, T. Panchal, S.P. Gorthi, V. Prabhu, A. Prabhu, V. Chandran, A. Chatterjee, R. Nair, V.K. Nambiar, D. TS, S. TP, V. Ajai, S. Paul, P.C. Natarajan, D. Chittibabu, N.C. Borah, M. Ghose, N. Choudhury, P. Gohain, K. Kalita, D. Duberkar, N. Pawar, R. Bhaviskar, E. Caterbi, S. Cenciarelli, R. Condurso, E. Gallinella, L. Greco, C. Marando, S. Mastrocola, A. Mattioni, E. Sacchini, I. Sicilia, A. Gallina, D. Giannandrea, E. Marsili, T. Mazzoli, C. Padiglioni, F. Corea, A. Guidubaldi, S. Micheli, M. Barbi, J. Kim, H.J. Song, H.S. Jeong, J.G. Lim, S.M. Park, K.B. Lee, H.W. Hwang, S.U. Kwon, D.W. Kang, Y.J. Kim, B.J. Kim, J.M. Park, K. Kang, B. Kim, O. Kwon, Y.W. Kim, J.J. Lee, Y.H. Hwang, H.S. Kwon, J. Koo, K. Lee, T. Kim, A. Ahn, J.H. Rha, H.K. Park, C.W. Yoon, B. Chan, H.L. Teoh, P. Paliwal, L.Y.J. Wong, J.T. Chen, D.A. De Silva, H.M. Chang, N. Fabiaña, J. Marti, R. Delgado, A. Martínez, L. Prats, P. Camps, C.W. Liou, T.Y. Tan, C.F. Liu, H.H. Cheng, H.L. Po, Y.J. Lin, C.L. Chou, C.H. Lin, C.C. Yen, Y.T. Chang, Y.T. Hsu, J.D. Lee, M. Lee, Y.C. Huang, C.Y. Wu, Y.C. Huang, N.C. Suwanwela, A. Chutinet, Y. Likitjaroen, D. Roongpiboonsopit, S. Charnwut, A. Dyker, M. Hossain, G.K. Muddegowda, R. Sanyal, C. Roffe, I. Natarajan, K. Finney, L. Sztriha, J. Teo, F.K. Chan, J. Lim, B. Chitando, B. Clarke, B. Patel, U. Khan, R. Ghatala, S. Trippier, L. Kalra, D. Manawadu, N. Sikondari, J. Aeron-Thomas, W. Sunman, G. Wilkes, C. Richardson, A. Buch, B. Jackson, O. Halse, S. Mashate, P. Wilding, V. Nguyen, M.R. Qadiri, K. Rashed, S. Board, C. Buckley, C. Smith, M. James, S. Keenan, A. Bouring, T. England, R. Donnelly, J. Scott, M. Maddula, J. Beavan, R. Perry, N. Francia, C. Watchhurst, A. Banaras, A. Ashton, A. Mistri, K. Musarrat, D. Eveson, J. Kallingal, J. Perez, L. Harrison, T. Marsden, J. Furnace, R. Clarke, J. Reid, E. Warburton, M.J. Macleod, J. Mitchell, D. Day, N. Church, E. Amis, C. Price, H. Rodgers, R. Whiting, M. Hussain, M. Harvey, S. Brown, J. Foot, D. Tryambake, D. Broughton, A. Bergin, A. Annamalai, L. Dixon, N. Weir, C. Blank, K. Harkness, A. Ali, E. Richards, K. Stocks, D.W. Bruce, M. Wani, T. Anjum, M. Krishnan, T. Nguyen Huy, A. Truong Le Tuan, L. Dam Thi Cam, T. Ngo Thi Kim, B. Pham Nguyen, A. Nguyen Dat, C. Nguyen Van, T. Mai Duy, P. Dao Viet, D. Nguyen Tien, T. Vo Van, K. Le Kim, T. Bui Ngoc, T. Tran Le Thanh, S. Nguyen Hoanh, S. Pham Phuoc, T. Tran Van, B. Doan Thi, H. Nguyen Thi Thu, M. Nguyen Duy, D. Ngo Van. Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial, The Lancet,
Volume 393, Issue 10174, 2019, Pages 877-888, ISSN 0140-6736,
https://doi.org/10.1016/S0140-6736(19)30038-8.
Keywords
item.page.dc.rights
item.page.dc.rights.url
Estadísticas de uso
1 0,8 0,5 0,3 0
Septiembre 2025Octubre 2025Noviembre 2025Diciembre 2025Enero 2026Febrero 2026Marzo 2026