Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness

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Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness.pdf (788.26 KB)

Date

2016

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Artículo

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Artículos Medicina y Ciencias de la Salud

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139

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2
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Springer

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http://hdl.handle.net/11447/912
 http://dx.doi.org/ 10.1007/s00424-016-1788-7

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Abstract

Gap-junction channels (GJCs) are formed by head-to-head association of two hemichannels (HCs, connexin hexamers). HCs and GJCs are permeable to ions and hydrophilic molecules of up to Mr ~1 kDa. Heari...

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Centro de Fisiología Celular e Integrativa

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Citation

Dalamon V, Fiori MC, Figueroa VA, Oliva CA, Del Rio R, Gonzalez W, Canan J, Elgoyhen AB, Altenberg GA, Retamal MA. Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness. Pflugers Arch. 2016 May;468(5):909-18.

Keywords

Deafness , Hemichannels , Connexins , Gap-junction channels , Ion channel , Mutation

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