In-Hospital Acute Ischemic Stroke is Associated with Worse Outcome: Experience of a Single Center in Santiago Chile

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dc.contributor.authorBrunser, Alejandro
dc.contributor.authorNavia, Víctor
dc.contributor.authorAraneda, Patricia
dc.contributor.authorMazzon, Enrico
dc.contributor.authorMuñoz Venturelli, Paula
dc.contributor.authorCavada, Gabriel
dc.contributor.authorOlavarría, Verónica
dc.contributor.authorLavados, Pablo
dc.date.accessioned2021-11-26T20:20:26Z
dc.date.available2021-11-26T20:20:26Z
dc.date.issued2021
dc.description.abstractObjectives: In-hospital acute ischemic stroke (HIS) accounts for 217% of all acute ischemic strokes (AIS) seen in hospital and they have worse prognosis. In this study we aimed to identify the frequency of HIS and their characteristics in our center. Materials and Methods: Retrospective analysis of a prospective register of patients with AIS seen at Clínica Alemana de Santiago, between January 2017 and January 2019. HIS and community onset ischemic strokes patients (CIS) were compared, univariate analysis was performed, covariates with p < 0.25 were selected for multivariate analysis. Differences between, proportion of strokes treated with thrombolytic therapy, door to needle time were compared between HIS and CIS patients, as also mortality rates at 90 days. Results: During the study period 369 patients with AIS were seen; of these 20 (5.4%, 95 CI%, 3.58.2) corresponded to HIS. In univariate analysis, HIS compared to patients arriving form the community to the emergency room, suffered more frequently from, heart failure (p = 0.04), and active malignancies (p < 0.001). HIS patients had longer times from symptom onset to non-contrast brain tomography (540 §150 minutes); they were also less frequently treated with intravenous thrombolysis compared to community AIS: 15% versus 30% respectively (p = 0.08). Mortality rates at 90 days were higher in HIS: 30 versus 5% (p = 0.001). Conclusions: In this cohort, HIS patients suffered delays in their neuroimaging studies and received less intravenous thrombolysis; this underscores the need for a standardized approach to the recognition and management of inhospital acute ischemic strokees
dc.identifier.citationBrunser A, Navia V V, Araneda P, Mazzon E, Muñoz P, Cavada G, Olavarría VV, Lavados PM. In-Hospital Acute Ischemic Stroke is Associated with Worse Outcome: Experience of a Single Center in Santiago Chile. J Stroke Cerebrovasc Dis. 2021 Aug;30(8):105894es
dc.identifier.urihttps://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2021.105894.es
dc.identifier.urihttp://hdl.handle.net/11447/5125
dc.language.isoenes
dc.subjectIn-hospital onset strokees
dc.subjectOutcomees
dc.subjectStrokees
dc.subjectStroke and cerebrovasculares
dc.titleIn-Hospital Acute Ischemic Stroke is Associated with Worse Outcome: Experience of a Single Center in Santiago Chilees
dc.typeArticlees

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