Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 Treated with Tocilizumab

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dc.contributor.authorNiño, Carmen
dc.contributor.authorEspinosa, Yazmín
dc.contributor.authorOtaola, Hugo
dc.contributor.authorPoli, Cecilia
dc.contributor.authorTapia, Lorena
dc.contributor.authorOrtiz, Paula
dc.date.accessioned2022-08-18T17:55:48Z
dc.date.available2022-08-18T17:55:48Z
dc.date.issued2020
dc.description.abstractWe describe a case of Pediatric Inflammatory Multisystem Syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in an 8-year-old child. The patient developed multiorgan dysfunction, including mixed shock, cardiac dysfunction with myocarditis, pneumonia, acute kidney failure, and gastrointestinal involvement characterized by inflammation of the wall of the bowel and pancreatitis. After treatment with Tocilizumab and corticoid therapy, he presented clinical improvement and normalization of inflammatory markers. PIMS-TS is a new disease developed in a small percentage of patients, so a high degree of suspicion is necessary to establish the diagnosis. Supportive care is of paramount importance. The use of Tocilizumab to control the inflammatory response is likely to be beneficial, but the best immunotherapeutic agent has not yet been established. Randomized clinical studies should be run to determine the best treatment.es
dc.description.versionVersión publicadaes
dc.identifier.citationNiño-Taravilla C, Espinosa-Vielma YP, Otaola-Arca H, Poli-Harlowe C, Tapia LI, Ortiz-Fritz P. Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 Treated with Tocilizumab. Pediatr Rep. 2020 Dec 4;12(3):142-148. doi:10.3390/pediatric12030029es
dc.identifier.urihttps://doi.org/doi:10.3390/pediatric12030029es
dc.identifier.urihttp://hdl.handle.net/11447/6531
dc.language.isoenes
dc.subjectMIS-Ces
dc.subjectPIMS-TSes
dc.subjectSARS-COV-2es
dc.subjectTocilizumabes
dc.titlePediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 Treated with Tocilizumabes
dc.typeArticlees
dcterms.sourcePediatric reportses

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