Permanent group effect on nucleofugality in aryl benzoates

dc.contributor.author	Campodónico, Paola
dc.contributor.author	Ormazábal-Toledo, Rodrigo
dc.contributor.author	Aizman, Arie
dc.contributor.author	Contreras, Renato
dc.date.accessioned	2021-10-25T13:00:03Z
dc.date.available	2021-10-25T13:00:03Z
dc.date.issued	2010
dc.description.abstract	We herein report on the group electrophilicity of molecular fragments present in the title compounds to describe leaving group abilities in reactions of aryl benzoates toward CN. It is found that the presence of electron-withdrawing substituents in the permanent group enhances its electrophilicity, thereby contributing to the stabilization of the tetrahedral intermediate involved in the stepwise pathway. On the other hand electron-releasing substituents attached to the permanent group enhance the nucleofugality of the leaving groups in these systems. Substituent effects are used to rationalize the activation/deactivation patterns induced by electron-withdrawing and electron-releasing groups at the aromatic rings.	es
dc.identifier.citation	Chemical Physics Letters 498 (2010) 221–225	es
dc.identifier.uri	https://doi.org/10.1016/j.cplett.2010.08.043	es
dc.identifier.uri	http://hdl.handle.net/11447/4890
dc.language.iso	en_US	es
dc.title	Permanent group effect on nucleofugality in aryl benzoates	es
dc.title.alternative	Efecto de grupo permanente sobre la nucleofugalidad en benzoatos de arilo	es
dc.type	Article	es

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