Myoclonus: An Electrophysiological Diagnosis

dc.contributor.authorMerchant, Shabbir Hussain I.
dc.contributor.authorVial Undurraga, Felipe
dc.contributor.authorLeodori, Giorgio
dc.contributor.authorGerpen, Jay A. van
dc.contributor.authorHallett, Mark
dc.date.accessioned2021-08-20T14:02:42Z
dc.date.available2021-08-20T14:02:42Z
dc.date.issued2020
dc.description.abstractBackground: Background Many different movement disorders have similar “jerk-like” phenomenology and can be misconstrued as myoclonus. Different types of myoclonus also share similar phenomenological characteristics that can be difficult to distinguish solely based on clinical exam. However, they have distinctive physiologic characteristics that can help refine categorization of jerk-like movements. Objectives: Objectives In this review, we briefly summarize the clinical, physiologic, and pathophysiologic characteristics of different types of myoclonus. The methodology and technical considerations for the electrophysiologic assessment of jerk-like movements are reviewed. A simplistic pragmatic approach for the classification of myoclonus and other jerk-like movements based on objective electrophysiologic characteristics is proposed. Conclusions: Conclusions Clinical neurophysiology is an underutilized tool in the diagnosis and treatment of movement disorders. Various jerk-like movements have distinguishing physiologic characteristics, differentiated in the milliseconds range, which is beyond human capacity. We argue that the categorization of movement disorders as myoclonus can be refined based on objective physiology that can have important prognostic and therapeutic implications.es
dc.identifier.citationMovement Disorders Clinical Practice, 2020, vol.7(5): 489–499es
dc.identifier.urihttps://dx.doi.org/ 10.1002/mdc3.12986es
dc.identifier.urihttp://hdl.handle.net/11447/4383
dc.language.isoenes
dc.subjectMyoclonuses
dc.subjectStartlees
dc.subjectJerk-like movementses
dc.subjectElectrophysiologyes
dc.titleMyoclonus: An Electrophysiological Diagnosises
dc.typeArticlees

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