Demographics, socio-economic characteristics, and risk factor prevalence in patients with non-cardioembolic ischaemic stroke in low- and middle-income countries: the OPTIC registry.

Simple item page
dc.contributor.authorAbboud, Halim
dc.contributor.authorLabreuche, Julien
dc.contributor.authorArauz, Antonio
dc.contributor.authorBryer, Alan
dc.contributor.authorLavados, Pablo
dc.contributor.authorMassaro, Ayrton
dc.contributor.authorMuñoz, Mario
dc.contributor.authorSteg, Philippe
dc.contributor.authorYamout, Bassem
dc.contributor.authorVicaut, Eric
dc.contributor.authorAmarenco, Pierre
dc.date.accessioned2017-04-10T13:58:47Z
dc.date.available2017-04-10T13:58:47Z
dc.date.issued2013
dc.description.abstractBACKGROUND: There is a paucity of data on patients with stroke/transient ischaemic attack in low- and middle-income countries. We sought to describe the characteristics and management of patients with an ischaemic stroke and recent transient ischaemic attack or minor ischaemic strokes in low- or middle-income countries. METHODS: The Outcomes in Patients with TIA and Cerebrovascular disease registry is an international, prospective study. Patients ≥ 45 years who required secondary prevention of stroke (either following an acute transient ischaemic attack or minor ischaemic strokes (National Institutes of Health Stroke Scale <4) of <24 h duration, or recent (<6 months), stable, first-ever, non-disabling ischaemic stroke) were enrolled in 17 countries in Latin America, the Middle East, and Africa. The main measures of interest were risk factors, comorbidities, and socio-economic variables. RESULTS: Between January 2007 and December 2008, 3635 patients were enrolled in Latin America (n = 1543), the Middle East (n = 1041), North Africa (n = 834), and South Africa (n = 217). Of these, 63% had a stable, first-ever ischaemic stroke (median delay from symptom onset to inclusion, 25 days interquartile range, 7-77); 37% had an acute transient ischaemic attack or minor ischaemic stroke (median delay, two-days; interquartile range, 0-6). Prevalence of diabetes was 46% in the Middle East, 29% in Latin America, 35% in South Africa, and 38% in North Africa; 72% had abdominal obesity (range, 65-78%; adjusted P < 0.001); prevalence of metabolic syndrome was 78% (range, 72-84%, P < 0.001). Abnormal ankle brachial index (<0.9) was present in 22%, peripheral artery disease in 7.6%, and coronary artery disease in 13%. Overall, 24% of patients had no health insurance and 27% had a low educational level. INTERPRETATION: In this study, patients in low- and middle-income countries had a high burden of modifiable risk factors. High rates of low educational level and lack of health insurance in certain regions are potential obstacles to risk factor control. FUNDING: The Outcomes in Patients with TIA and Cerebrovascular disease registry is supported by Sanofi-Aventis, Paris, France.
dc.format.extent10
dc.identifier.citationInt J Stroke. 2013 Oct;8 Suppl A100:4-13
dc.identifier.urihttp://hdl.handle.net/11447/1121
dc.identifier.urihttp://dx.doi.org/10.1111/j.1747-4949.2012.00893.x
dc.language.isoen_US
dc.publisherSage Publications
dc.subjectdeveloping countries
dc.subjectepidemiology
dc.subjectprevention
dc.subjectrisk factors
dc.subjectsocio-economic factors
dc.subjectstroke
dc.titleDemographics, socio-economic characteristics, and risk factor prevalence in patients with non-cardioembolic ischaemic stroke in low- and middle-income countries: the OPTIC registry.
dc.typeArtículo

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Demographics, socio-economic characteristics, and risk.pdf
Size:
394.35 KB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services