Determinantes del tiempo puerta-aguja en trombolisis endovenosa en el infarto cerebral, experiencia de un centro

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dc.contributor.authorBrunser, Alejandro
dc.contributor.authorMazzon, Enrico
dc.contributor.authorMuñoz, Paula
dc.contributor.authorHoppe, Arnold
dc.contributor.authorLavados, Pablo
dc.contributor.authorRojo, Alexis
dc.contributor.authorNavia, Víctor
dc.contributor.authorCavada, Gabriel
dc.contributor.authorOlavarría, Verónica
dc.contributor.authorMansilla, Eloy
dc.date.accessioned2021-08-23T21:40:17Z
dc.date.available2021-08-23T21:40:17Z
dc.date.issued2020
dc.description.abstractBackground: Intravenous thrombolysis (IT) in acute ischemic stroke (AIS) is time dependent. The time elapsed from hospital admission to the thrombolytic bolus is named door to needle time (DNT) and is recommend to be of less than 60 min. Aim: To describe the DNT in our center and determine those factors associated with a DNT longer than 60 min. Material and Methods: Prospective analysis of patients treated with IT at a private hospital between June 2016 and June 2019. The percentage of patients with DNT exceeding 60 min, and the causes for this delay were evaluated. Results: IT was used in 205 patients. DNT was 43.6 ± 23.8 min. Forty patients (19.5% (95% CI, 14.4-25.7), had a DNT longer than 60 min. Uni-varied analysis demonstrated that AIS with infratentorial symptomatology (ITS), was significantly associated with DNTs exceeding 60 min. A history of hypertension, a higher NIH Stroke Scale score, the presence of an hyperdense sign in brain tomography (p = 0.001) and the need for endovascular therapy (p = 0.019), were associated with DNT shorter than 60 min. Multivariate analysis ratified the relationship between ITS and DNT longer than 60 min (Odds ratio: 3.19, 95% confidence intervals 1.26-8). Conclusions: The individual elements that correlated with a DNT longer than 60 min were the failure to detect the AIS during triage and doubts about its diagnosises
dc.identifier.citationRevista Médica de Chile, 2020, vol.148(8): 1090-1095es
dc.identifier.urihttps://dx.doi.org/10.4067/S0034-98872020000801090es
dc.identifier.urihttp://hdl.handle.net/11447/4434
dc.language.isoeses
dc.subjectStrokees
dc.subjectTriagees
dc.subjectThrombolytic Therapyes
dc.titleDeterminantes del tiempo puerta-aguja en trombolisis endovenosa en el infarto cerebral, experiencia de un centroes
dc.title.alternativeDeterminants of door to needle time for intravenous thrombolysis in acute ischemic strokees
dc.typeArticlees

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