A novel exaggerated "Spino-bulbo-spinal like" reflex of lower brainstem origin

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dc.contributor.authorMerchant, Shabbir Hussain
dc.contributor.authorVial Undurraga, Felipe
dc.contributor.authorLeodori, Giorgio
dc.contributor.authorFahn, Stanley
dc.contributor.authorPullman, Seth
dc.contributor.authorHallett, Mark
dc.date.accessioned2019-08-13T22:16:01Z
dc.date.available2019-08-13T22:16:01Z
dc.date.issued2019
dc.description.abstractBackground: Many different oligosynaptic reflexes are known to originate in the lower brainstem which share phenomenological and neurophysiological similarities. Objective: To evaluate and discuss the differences and aberrancies among these reflexes, which are hard to discern clinically using neurophysiological investigations with the help of a case report. Methods: We describe the clinical and neurophysiological assessment of a young man who had a childhood history of opsoclonus-myoclonus syndrome with residual mild ataxia and myoclonic jerks in the distal extremities presenting with subacute onset total body jerks sensitive to sound and touch (in a limited dermatomal distribution), refractory to medications. Results: Based on clinical characteristics and insights gained from neurophysiological testing we could identify a novel reflex of caudal brainstem origin. Conclusions: The reflex described is likely an exaggerated normal reflex, likely triggered by a dolichoectatic vertebral arterial compression and shares characteristics of different reflexes known to originate in caudal brainstem, which subserve distinctive roles in human postural control
dc.format.extent38 p.
dc.identifier.citationParkinsonism and Related Disorders. 2019 Apr.
dc.identifier.urihttp://hdl.handle.net/11447/2579
dc.identifier.urihttp://dx.doi.org/10.1016/j.parkreldis.2018.10.007
dc.language.isoen
dc.subjectJerk-like movements
dc.subjectMyoclonus
dc.subjectPhysiology
dc.subjectReflex
dc.subjectStartle
dc.titleA novel exaggerated "Spino-bulbo-spinal like" reflex of lower brainstem origin
dc.typeArticle

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