Regulation of Intercellular Calcium Signaling Through Calcium Interactions with Connexin-Based Channels

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dc.contributor.authorOrellana, Juan
dc.contributor.authorSánchez, Helmuth
dc.contributor.authorSchalper, Kurt
dc.contributor.authorFigueroa, Vania
dc.contributor.authorSáez, Juan
dc.date.accessioned2021-10-03T03:37:16Z
dc.date.available2021-10-03T03:37:16Z
dc.date.issued2012
dc.description.abstractThe synchronization of numerous cellular events requires complex electric and metabolic cell-cell interactions. Connexins are a family of membrane proteins that constitute the molecular basis of two kinds of channels: gap junction channels (GJCs), which allow direct cytoplasm-cytoplasm communication, and hemichannels (HCs) that provide a pathway for exchanges between the intra and extra-cellular milieu. Both kind of connexin-based channels support intercellular communication via intercellular propagation of calcium waves. Here, we review evidence supporting the role of Ca 2+ in the regulation of GJCs and HCs formed by connexins. Also it is speculated how these connexin-based channels could contribute to the propagation of intercellular Ca 2+ signals.es
dc.identifier.citationEn: Islam M. (eds) Calcium Signaling. Advances in Experimental Medicine and Biology, 2012; 777-794,740. Springer, Dordrechtes
dc.identifier.urihttps://dx.doi.org/10.1007/978-94-007-2888-2_34es
dc.identifier.urihttp://hdl.handle.net/11447/4770
dc.language.isoenes
dc.subjectHemichannelses
dc.subjectGap junctionses
dc.subjectConnexonses
dc.subjectCalcium waveses
dc.subjectDye couplinges
dc.subjectCalmodulines
dc.titleRegulation of Intercellular Calcium Signaling Through Calcium Interactions with Connexin-Based Channelses
dc.typeBook chapteres

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