Shock séptico en la Unidad de Cuidados Intensivos. Terapéutica avanzada, inmunoparálisis y genómica. Estado del arte

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dc.contributor.authorArriagada, Daniela
dc.contributor.authorDonoso, Alejandro
dc.contributor.authorCruces, Pablo
dc.contributor.authorDíaz, Franco
dc.date.accessioned2017-03-31T15:50:29Z
dc.date.available2017-03-31T15:50:29Z
dc.date.issued2014
dc.description.abstractNew and important concepts have emerged for the advanced management of the child with septic shock in the recent decades. Attending physicians in the Pediatric intensive care unit must be fully aware of them to improve patient care in the critical care unit. It should be considered the use of immune therapy only in selected groups of patients. Continuous renal replacement therapies are well tolerated and their early use prevents deleterious fluid overload. Removal of inflammatory mediators by using high volume hemofiltration may play a role in hyperdynamic septic patients. The use of plasmapheresis is recommended in patients with thrombocytopenia-associated multiple organ failure. Extracorporeal support use should be considered in those with refractory septic shock despite goals directed therapy. The immunoparalysis has been associated with nosocomial infections and late mortality. The information from genetic markers may allow early intervention and preventive genomics-based medicine.
dc.format.extent8
dc.identifier.citationArch Argent Pediatr 2014;112(4):358-365
dc.identifier.urihttp://hdl.handle.net/11447/1076
dc.identifier.urihttp://dx.doi.org/10.1590/S0325-00752014000400012
dc.language.isoen_US
dc.publisherSociedad Argentina de Pediatría
dc.subjectsepsis
dc.subjectseptic shock
dc.subjecttreatment
dc.subjectresuscitation
dc.subjectextracorporeal support
dc.subjectimmunoparalysis
dc.subjectgenomics
dc.titleShock séptico en la Unidad de Cuidados Intensivos. Terapéutica avanzada, inmunoparálisis y genómica. Estado del arte
dc.title.alternativeSeptic shock in ICU: Advanced therapeutics, immunoparalysis and genomics. State of the art
dc.typeArtículo

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