Survival of Critically Ill Oncologic Patients Requiring Invasive Ventilatory Support: A Prospective Comparative Cohort Study With Nononcologic Patients

Simple item page
dc.contributor.authorLópez, René
dc.contributor.authorPérez-Araos, Rodrigo
dc.contributor.authorSamtani, Suraj
dc.contributor.authorMontes, José Miguel
dc.contributor.authorPérez, Rodrigo
dc.contributor.authorMartin, María José
dc.contributor.authorSalazar, Álvaro
dc.contributor.authorGraf, Jeronimo
dc.date.accessioned2022-03-25T19:16:41Z
dc.date.available2022-03-25T19:16:41Z
dc.date.issued2019
dc.description.abstractPurpose: Cancer is in the process of changing to become a chronic disease; therefore, an increasing number of oncologic patients (OPs) are being admitted to intensive care units (ICUs) for supportive care of disease or therapy-related complications. We compare the short- and long-term outcomes of critically ill mechanically ventilated OPs with those of their nononcologic counterparts. Patients and methods: We performed a prospective study of patients admitted to our ICU between October 2017 and February 2019. Demographic, physiologic, laboratory, clinical, and treatment data were obtained. The primary outcome was survival at 28 days and at the end of the follow-up period. Secondary outcomes were survival according to acute severity scoring (Acute Physiology and Chronic Health Evaluation II score), Eastern Cooperative Oncology Group (ECOG) performance status, and Charlson comorbidity index. Results: A total of 1,490 patients were admitted during the study period; 358 patients (24%) were OPs, and 100 of these OPs were supported with mechanical ventilation. Seventy-three percent of OPs had an ECOG performances status of 0 or 1, and 90% had solid tumors. Reason for admission to the ICU was postoperative admission in 44 patients and neutropenic infection in 10 patients. The follow-up period was 148 days (range, 42 to 363 days). Survival at 28 days was similar between OPs and nononcologic patients and associated with the Acute Physiology and Chronic Health Evaluation II score. However, long-term survival was lower in OPs compared with nononcologic patients (52% v 76%, respectively; P < .001) and associated with poor ECOG performance status. Conclusion: Short-term survival of critically ill, mechanically ventilated OPs is similar to that of their nononcologic counterparts and is determined by the severity of the critical illness.es
dc.description.versionVersión publicadaes
dc.identifier.citationLópez R, Samtani SR, Montes JM, Perez R, Martin MJ, Salazar A, Graf J. Survival of Critically Ill Oncologic Patients Requiring Invasive Ventilatory Support: A Prospective Comparative Cohort Study With Nononcologic Patients. J Glob Oncol. 2019 Sep;5:1-8. doi: 10.1200/JGO.19.00184es
dc.identifier.urihttps://doi.org//10.1200/JGO.19.00184es
dc.identifier.urihttp://hdl.handle.net/11447/5806
dc.language.isoenes
dc.subjectCohort Studieses
dc.subjectCritical Illness / rehabilitationes
dc.subjectFemalees
dc.subjectHumanses
dc.subjectMedical Oncology / methodses
dc.subjectMiddle Agedes
dc.subjectProspective Studieses
dc.subjectRespiration, Artificial / methodses
dc.subjectSurvival Analysises
dc.titleSurvival of Critically Ill Oncologic Patients Requiring Invasive Ventilatory Support: A Prospective Comparative Cohort Study With Nononcologic Patientses
dc.typeArticlees
dcterms.sourceJournal of global oncologyes

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Survival of Critically Ill Oncologic Patients.pdf
Size:
712.54 KB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services