Heterogeneity Among Poor Ovarian Responders According to Bologna Criteria Results in Diverging Cumulative Live Birth Rates

Simple item page
dc.contributor.authorRomito, Alessia
dc.contributor.authorErrázuriz, Joaquín
dc.contributor.authorBardhi, Erlisa
dc.contributor.authorBlockeel, Christophe
dc.contributor.authorSantos-Ribeiro, Samuel
dc.contributor.authorDe Vos, Michel
dc.contributor.authorRacca, Annalisa
dc.contributor.authorMackens, Shari
dc.contributor.authorBenedetti Panici, Pierluigi
dc.contributor.authorVaiarelli, Alberto
dc.contributor.authorTournaye, Herman
dc.contributor.authorDrakopoulos, Panagiotis
dc.contributor.authorVan Der Kelen, Annelore
dc.contributor.authorBenedett, Pierluigi
dc.date.accessioned2021-07-14T20:00:01Z
dc.date.available2021-07-14T20:00:01Z
dc.date.issued2020-04
dc.description.abstractResearch Question: Does reproductive outcome differ among the various subgroups of poor ovarian responders according to the Bologna criteria? Design: This was a retrospective, cohort study including poor ovarian responders according to Bologna criteria, undergoing an ICSI cycle from January 2011 until December 2017. Patients were divided into four groups: (1) age ≥ 40 years and abnormal ovarian response test, (2) age ≥ 40 years, abnormal ovarian reserve test and one previous poor response to stimulation, (3) age ≥ 40 years and one previous poor response, (4) abnormal ovarian reserve test and one previous poor response. Result(s): Overall, 846 cycles in 706 Bologna poor ovarian responders were included: 310 cycles in group 1, 169 in group 2, 52 in group 3, and 315 in group 4. There were significant differences in age, antral follicle count, antimüllerian hormone, cycle cancellation rates, and number of retrieved oocytes between the four groups. Live birth and cumulative live birth rate differed significantly between groups and were highest in Group 4 [Live birth rate: 7.4% (1) vs. 4.1% (2) vs. 5.8% (3) vs. 13.4% (4), p = 0.001 and Cumulative live birth rate: 8.3% (1) vs. 4.1 % (2) vs. 9.6% (3) vs. 16.8% (4) p < 0.001]. The multivariate GEE analysis revealed that the number of MIIs and the Bologna criteria pattern were the variables which were significantly associated with cumulative live birth rate. Conclusion(s): Poor ovarian responders represent a heterogeneous population. The young subpopulation has a better clinical prognosis in terms of fresh and cumulative live birth rate.es
dc.identifier.citationFrontiers in Endocrinology, 2020, vol.11, art. 208es
dc.identifier.urihttps://doi.org/10.3389/fendo.2020.00208es
dc.identifier.urihttp://hdl.handle.net/11447/4186
dc.language.isoenes
dc.subjectBologna criteriaes
dc.subjectICSIes
dc.subjectCumulative live birth ratees
dc.subjectPoor ovarian responsees
dc.subjectPoor responderses
dc.titleHeterogeneity Among Poor Ovarian Responders According to Bologna Criteria Results in Diverging Cumulative Live Birth Rateses
dc.typeArticlees

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Heterogeneity Among Poor Ovarian Respon... Diverging Cumulative Live Birth Rates.pdf
Size:
443.88 KB
Format:
Adobe Portable Document Format
Description:
Texto completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services