Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions

dc.contributor.author	Munita, José
dc.contributor.author	Mishra, Nagendra N.
dc.contributor.author	Alvarez, Danya
dc.contributor.author	Tran, Truc T
dc.contributor.author	Diaz, Lorena
dc.contributor.author	Panesso, Diana
dc.contributor.author	Reyes, Jinnethe
dc.contributor.author	Murray, Barbara E
dc.contributor.author	Adachi, Javier A
dc.contributor.author	Bayer, Arnold S
dc.contributor.author	Arias, Cesar A
dc.date.accessioned	2021-11-03T16:51:25Z
dc.date.available	2021-11-03T16:51:25Z
dc.date.issued	2014
dc.description.abstract	High-dose daptomycin (DAP) therapy failed in a neutropenic patient with bloodstream infection caused by a DAP-susceptible Enterococcus faecium (minimum inhibitory concentration, 3 µg/mL) harboring genetic changes associated with DAP resistance, with persistent bacteremia and selection of additional resistances. Daptomycin monotherapy should be used cautiously against DAP-susceptible E. faecium strains with minimum inhibitory concentrations >2 µg/mL.	es
dc.identifier.citation	Clinical Infectious Diseases, 2014, 59(9):1277-80	es
dc.identifier.uri	http://dx.doi.org/10.1093/cid/ciu642	es
dc.identifier.uri	http://hdl.handle.net/11447/5007
dc.language.iso	en	es
dc.subject	Enterococcus faecium	es
dc.subject	Daptomycin	es
dc.subject	Resistance	es
dc.subject	Treatment failure	es
dc.title	Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions	es
dc.type	Article	es

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