Human reciprocity: behavioural components and neurocognitive signatures discriminating outcomes and intentions in trust-repayment behaviour – and some evolutionary considerations

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dc.contributor.advisorBilleke, Pablo
dc.contributor.advisorRodríguez-Sickert, Carlos
dc.contributor.authorAspé Sánchez, Mauricio
dc.date.accessioned2020-10-01T18:05:15Z
dc.date.available2020-10-01T18:05:15Z
dc.date.issued2020-09
dc.descriptionTesis presentada a la Facultad de Gobierno de la Universidad del Desarrollo para optar al grado académico de Doctor en Ciencias de la Complejidad Sociales
dc.description.abstractOxytocin (OXT) and arginine-vasopressin (AVP) are two phylogenetically conserved neuropeptides that have been implicated in a wide range of social behaviors. Although a large body of research, ranging from rodents to humans, has reported on the effects of OXT and AVP administration on affiliative and trust behaviors, and has highlighted the genetic contributions of OXT and AVP receptor polymorphisms to both social behaviors and to diseases related to social deficits, the consequences of peptide administration on psychiatric symptoms, and the impact of receptor polymorphisms on receptor function, are still unclear. Despite the exciting advances that these reports have brought to social neuroscience, they remain preliminary and suffer from the problems that are inherent to monogenetic linkage and association studies. As an alternative, some studies are using polygenic approaches, and consider the contributions of other genes and pathways, including those involving DA, 5-HT, and reelin, in addition to OXT and AVP; a handful of report are also using genome-wide association studies. This review summarizes findings on the associations between OXT and AVP receptor polymorphism, social behavior, and psychiatric diseases. In addition, we discuss reports on the interactions of OXT and AVP receptor genes and genes involved in other pathways (like those of dopamine, serotonin, and reelin), as well as research that has shed some light on the impact of gene polymorphisms on the volume, connectivity, and activation of specific neural structures, differential receptor expression, and plasma levels of the OXT and AVP peptides. We hope that this effort will be helpful for understanding the studies performed so far, and for encouraging the inclusion of other candidate genes not explored to date.es
dc.format.extent209 p.es
dc.identifier.doihttp://doi.org/10.52611/11447/3454
dc.identifier.urihttp://repositorio.udd.cl/handle/11447/3454
dc.language.isoenes
dc.publisherUniversidad del Desarrollo. Facultad de Gobiernoes
dc.subjectAltruismes
dc.subjectElectroencephalographyes
dc.subjectNeocortexes
dc.subjectCognitive control systemes
dc.subjectHuman socialityes
dc.subject060005S
dc.titleHuman reciprocity: behavioural components and neurocognitive signatures discriminating outcomes and intentions in trust-repayment behaviour – and some evolutionary considerationses
dc.typeThesises
dcterms.accessRightsAcceso abierto

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