Metastatic pulmonary calcification: High-resolution computed tomography findings in 23 cases

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dc.contributor.authorBelém, Luciana
dc.contributor.authorSouza, Carolina
dc.contributor.authorSouza, Arthur
dc.contributor.authorEscuissato, Dante
dc.contributor.authorHochhegger, Bruno
dc.contributor.authorNobre, Luiz
dc.contributor.authorRodrigues, Rosana
dc.contributor.authorGomes, Antônio
dc.contributor.authorSilva, Claudio
dc.contributor.authorGuimarães, Marcos
dc.contributor.authorZanetti, Gláucia
dc.contributor.authorMarchiori, Edson
dc.date.accessioned2018-01-22T14:43:24Z
dc.date.available2018-01-22T14:43:24Z
dc.date.issued2017
dc.description.abstractOBJECTIVE: The aim of this study was to evaluate the high-resolution computed tomography (HRCT) findings in patients diagnosed with metastatic pulmonary calcification (MPC). MATERIALS AND METHODS: We retrospectively reviewed the HRCT findings from 23 cases of MPC [14 men, 9 women; mean age, 54.3 (range, 26-89) years]. The patients were examined between 2000 and 2014 in nine tertiary hospitals in Brazil, Chile, and Canada. Diagnoses were established by histopathologic study in 18 patients and clinical-radiological correlation in 5 patients. Two chest radiologists analyzed the images and reached decisions by consensus. RESULTS: The predominant HRCT findings were centrilobular ground-glass nodules (n = 14; 60.9%), consolidation with high attenuation (n = 10; 43.5%), small dense nodules (n = 9; 39.1%), peripheral reticular opacities associated with small calcified nodules (n = 5; 21.7%), and ground-glass opacities without centrilobular ground-glass nodular opacity (n = 5; 21.7%). Vascular calcification within the chest wall was found in four cases and pleural effusion was observed in five cases. The abnormalities were bilateral in 21 cases. CONCLUSION: MPC manifested with three main patterns on HRCT, most commonly centrilobular ground-glass nodules, often containing calcifications, followed by dense consolidation and small solid nodules, most of which were calcified. We also described another pattern of peripheral reticular opacities associated with small calcified nodules. These findings should suggest the diagnosis of MPC in the setting of hypercalcemia.
dc.description.versionVersión Publicada
dc.format.extent6
dc.identifier.citationRadiol Bras. 2017 Jul-Aug;50(4):231-236
dc.identifier.urihttp://hdl.handle.net/11447/1930
dc.identifier.urihttp://dx.doi.org/10.1590/0100-3984.2016-0123
dc.language.isoen_US
dc.publisherColegio Brasileiro De Radiologia
dc.sourceRadiologia Brasileira
dc.subjectComputed tomography
dc.subjectMetabolic diseases
dc.subjectMetastatic pulmonary calcification
dc.subjectPulmonary diseases
dc.titleMetastatic pulmonary calcification: High-resolution computed tomography findings in 23 cases
dc.title.alternativeCalcificação pulmonar metastática: achados na tomografia computadorizada de alta resolução de 23 casos
dc.typeArtículo

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