Rationale of Therapeutic Plasma Exchange as Rescue Immunomodulatory Treatment for MIS-C With Multiorgan Failure
Date
2021
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Article
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Abstract
Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 infection is an infrequent and poorly understood illness. It can present as severe multiorgan failure in children, potentially lethal. Immunomodulation is the empiric treatment because a dysregulated immune response is the primary pathophysiologic mechanism. We present an infant with severe MIS-C, refractory to usual treatment, successfully treated with plasmapheresis.
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Citation
Díaz F, Cores C, Atenas O, Rodríguez N, Bustos R, Cruces P. Rationale of Therapeutic Plasma Exchange as Rescue Immunomodulatory Treatment for MIS-C With Multiorgan Failure. Pediatr Infect Dis J. 2021 Jul 1;40(7):e259-e262. doi: 10.1097/INF.0000000000003169.
Keywords
MIS-C, COVID-19, Plasmapheresis