Morphine self-administration is inhibited by the antioxidant N‐acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration

Quintanilla, María Elena; Morales, Paola; Santapau, Daniela; Gallardo, Javiera; Rebolledo, Rocío; Riveras, Gabriel; Acuña, Tirso; Herrera-Marschitz, Mario; Israel, Yedy; Ezquer, Fernando

Publication:
Morphine self-administration is inhibited by the antioxidant N‐acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration

Files

journal.pone.0312828.pdf (3.06 MB)

Date

2024

Type:

Article

Collections

Artículos Medicina y Ciencias de la Salud

Descargas totales

149

Vistas totales

3

Métricas

Gestores bibliográficos

Authors

Quintanilla, María Elena

Morales, Paola

Santapau, Daniela

Gallardo, Javiera

Rebolledo, Rocío

Riveras, Gabriel

Acuña, Tirso

Herrera-Marschitz, Mario

Israel, Yedy

Ezquer, Fernando

item.page.doiurl

https://doi.org/10.1371/journal.pone.0312828

URI

https://hdl.handle.net/11447/10247

item.page.extent

22 p.

item.page.accessRights

Acceso abierto

Abstract

Background The treatment of opioid addiction mainly involves the medical administration of methadone or other opioids, aimed at gradually reducing dependence and, consequently, the need for illicit op...

Citation

Quintanilla ME, Morales P, Santapau D, Gallardo J, Rebolledo R, Riveras G, Acuña T, Herrera-Marschitz M, Israel Y, Ezquer F. Morphine self-administration is inhibited by the antioxidant N-acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration. PLoS One. 2024 Oct 29;19(10):e0312828. doi: 10.1371/journal.pone.0312828.

Keywords

Morphine dependence

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