Effects of socioeconomic status in cognition of people with schizophrenia: results from a Latin American collaboration network with 1175 subjects

dc.contributor.authorSanguinetti, Letícia
dc.contributor.authorAlliende, Luz Maria
dc.contributor.authorCastañeda, Carmen Paz
dc.contributor.authorCastro, Mariana
dc.contributor.authorGuinjoan, Salvador
dc.contributor.authorMassuda, Raffael
dc.contributor.authorBerberian, Arthur
dc.contributor.authorFonseca, Ana
dc.contributor.authorGadelha, Ary
dc.contributor.authorBressan, Rodrigo
dc.contributor.authorCrivelaro, Marisa
dc.contributor.authorLouzã, Mario
dc.contributor.authorUndurraga, Juan
dc.contributor.authorGonzález, Alfonso
dc.contributor.authorNacha, Rubén
dc.contributor.authorNieto, Rodrigo
dc.contributor.authorMontes, Cristian
dc.contributor.authorSilva, Hernán
dc.contributor.authorLanger, Álvaro
dc.contributor.authorSchmidt, Carlos
dc.contributor.authorMayol, Rocío
dc.contributor.authorDíaz, Ana
dc.contributor.authorValencia, Johanna
dc.contributor.authorLópez, Carlos
dc.contributor.authorSolís, Rodolfo
dc.contributor.authorReyes, Francisco
dc.contributor.authorDe la Fuente, Camilo
dc.contributor.authorCrossley, Nicolás
dc.contributor.authorGama, Clarissa
dc.date.accessioned2022-03-28T13:17:58Z
dc.date.available2022-03-28T13:17:58Z
dc.date.issued2021
dc.description.abstractBackground. Cognition heavily relies on social determinants and genetic background. Latin America comprises approximately 8% of the global population and faces unique challenges, many derived from specific demographic and socioeconomic variables, such as violence and inequality. While such factors have been described to influence mental health outcomes, no large-scale studies with Latin American population have been carried out. Therefore, we aim to describe the cognitive performance of a representative sample of Latin American individuals with schizophrenia and its relationship to clinical factors. Additionally, we aim to investigate how socioeconomic status (SES) relates to cognitive performance in patients and controls. Methods. We included 1175 participants from five Latin American countries (Argentina, Brazil, Chile, Colombia, and Mexico): 864 individuals with schizophrenia and 311 unaffected subjects. All participants were part of projects that included cognitive evaluation with MATRICS Consensus Cognitive Battery and clinical assessments. Results. Patients showed worse cognitive performance than controls across all domains. Age and diagnosis were independent predictors, indicating similar trajectories of cognitive aging for both patients and controls. The SES factors of education, parental education, and income were more related to cognition in patients than in controls. Cognition was also influenced by symptomatology. Conclusions. Patients did not show evidence of accelerated cognitive aging; however, they were most impacted by a lower SES suggestive of deprived environment than controls. These findings highlight the vulnerability of cognitive capacity in individuals with psychosis in face of demographic and socioeconomic factors in low- and middle-income countries.es
dc.description.versionVersión publicadaes
dc.identifier.citationCzepielewski LS, Alliende LM, Castañeda CP, Castro M, Guinjoan SM, Massuda R, Berberian AA, Fonseca AO, Gadelha A, Bressan R, Crivelaro M, Louzã M, Undurraga J, González-Valderrama A, Nachar R, Nieto RR, Montes C, Silva H, Langer ÁI, Schmidt C, Mayol-Troncoso R, Díaz-Zuluaga AM, Valencia-Echeverry J, López-Jaramillo C, Solís-Vivanco R, Reyes-Madrigal F, de la Fuente-Sandoval C, Crossley NA, Gama CS. Effects of socioeconomic status in cognition of people with schizophrenia: results from a Latin American collaboration network with 1175 subjects. Psychol Med. 2021 Jun 23:1-12. doi: 10.1017/S0033291721002403es
dc.identifier.urihttp://doi.org/10.1017/S0033291721002403es
dc.identifier.urihttp://hdl.handle.net/11447/5813
dc.language.isoenes
dc.subjectCognitiones
dc.subjectlowes
dc.subjectmiddle-income countrieses
dc.subjectschizophreniaes
dc.subjectsocial factorses
dc.titleEffects of socioeconomic status in cognition of people with schizophrenia: results from a Latin American collaboration network with 1175 subjectses
dc.typeArticlees
dcterms.sourcePsychological medicinees

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