Maternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chile

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dc.contributor.authorHaye, Maria Teresa
dc.contributor.authorCartes, Giorgia
dc.contributor.authorGutiérrez, Jorge
dc.contributor.authorAhumada, Paz
dc.contributor.authorKrause, Bernardo
dc.contributor.authorMerialdi, Mario
dc.contributor.authorGonzález, Rogelio
dc.date.accessioned2022-04-08T19:32:42Z
dc.date.available2022-04-08T19:32:42Z
dc.date.issued2021
dc.description.abstractObjective and methods: We conducted a prospective observational cohort study in 458 pregnant and puerperal women, with confirmed COVID-19 at Hospital San Jose, Santiago, Chile, to determine the impact of COVID-19 on pregnancy and confirm safety and feasibility of a management protocol based on clinical presentation of the disease. Results: 25.5% (117/458) of women were severe and 74.4% (341/458) mild presentation. Three percent (9/341) of mild presentations required a subsequent hospitalization. Overall, 26/458 women (5.6%) were admitted to ICU, and 13/458 (2.8%) required mechanical ventilation. One maternal death occurred at 49-days postpartum. Severe presentation, infection above 24 weeks, and comorbidities were associated with an adverse maternal outcome. Of total deliveries, 16.5% (36/217) were <37 weeks. Perinatal mortality was 6/226 (2.7%), mostly due to the fetal component. Conclusions: A quarter of the women had severe COVID-19 that, combined with occurrence of disease in the second half of pregnancy, resulted in substantial maternal compromise. Perinatal morbidity and mortality in women with severe disease were high and warrant consideration. Outpatient management was safe for mild cases.es
dc.description.versionVersión publicadaes
dc.identifier.citationHaye MT, Cartes G, Gutiérrez J, Ahumada P, Krause B, Merialdi M, Gonzalez R. Maternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chile. J Matern Fetal Neonatal Med. 2021 Apr 1:1-6. doi: 10.1080/14767058.2021.1902498es
dc.identifier.urihttps://doi.org/10.1080/14767058.2021.1902498es
dc.identifier.urihttp://hdl.handle.net/11447/5964
dc.language.isoenes
dc.subjectCOVID-19es
dc.subjectLatin Americaes
dc.subjectSARS-CoV-2es
dc.subjectIntensive care unites
dc.subjectPregnancyes
dc.titleMaternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chilees
dc.typeArticlees
dcterms.sourceJournal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricianses

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