Pediatric inflammatory multisystem syndrome associated with SARS-CoV-2: a case series quantitative systematic review

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dc.contributor.authorBustos B., Raúl
dc.contributor.authorJaramillo-Bustamante, Juan Camilo
dc.contributor.authorVásquez-Hoyos, Pablo
dc.contributor.authorCruces, Pablo
dc.contributor.authorDíaz, Franco
dc.date.accessioned2021-08-31T20:28:31Z
dc.date.available2021-08-31T20:28:31Z
dc.date.issued2021
dc.description.abstractPediatric inflammatory multisystem syndrome associated with SARS-CoV-2 (PIMS-TS) is infrequent, but children might present as a life-threatening disease. In a systematic quantitative review, we analyzed 11 studies PIMS-TS, including 468 children reported before Jul 1st. We found a myriad of clinical features, but we were able to describe common characteristics: previously healthy school-aged children, persistent fever and gastrointestinal symptoms, lymphopenia, and high inflammatory markers. Clinical syndromes like myocarditis and Kawasaki disease were present in only one-third of cases each one. PICU admission was frequent, although LOS was less than one week, and mortality was low. Most patients received immunoglobulin or steroids, although the level of evidence for that treatment is low. PIMS-ST was recently described, and the detailed quantitative pooled data will increase clinicians' awareness, improve diagnosis, and promptly start treatment. This analysis also highlights the necessity of future collaboratives studies, given the heterogeneous nature of PIMS-TS.es
dc.identifier.citationPediatric Emergency Care, 2021es
dc.identifier.urihttps://dx.doi.org/10.1097/PEC.0000000000002306es
dc.identifier.urihttp://hdl.handle.net/11447/4556
dc.language.isoenes
dc.subjectCOVID-19es
dc.subjectKawasakies
dc.subjectMIS-Ces
dc.subjectPIMS-TSes
dc.subjectHyperinflammatory syndromees
dc.titlePediatric inflammatory multisystem syndrome associated with SARS-CoV-2: a case series quantitative systematic reviewes
dc.typeArticlees

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