Systematic Reviews in Neonatal Respiratory Care: Are Some Conclusions Misleading?

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dc.contributor.authorMaturana, Andres
dc.contributor.authorMoya, Fernando
dc.contributor.authorDonn, Steven M.
dc.date.accessioned2021-10-26T13:44:04Z
dc.date.available2021-10-26T13:44:04Z
dc.date.issued2020
dc.description.abstractAn increasing amount of information is currently available in neonatal respiratory care. Systematic reviews are an important tool for clinical decision-making. The challenge is to combine studies that address a specific clinical question and have similar characteristics in terms of populations, interventions, comparators, and outcomes, so that their combined results provide a more precise estimate of the effect that can be validly extrapolated into clinical practice. The concept of heterogeneity is reviewed, emphasizing that it should be considered in a wider perspective and not just as a mere statistical test. A case is made of how well-designed studies of the neonatal respiratory literature, when equivocally combined, can provide very precise but potentially biased results. Systematic reviews in this field and others should be rigorously peer-reviewed before publication to avoid misleading readers to potentially biased conclusions.es
dc.identifier.citationMaturana A, Moya F and Donn SM (2020) Systematic Reviews in Neonatal Respiratory Care: Are Some Conclusions Misleading? Front. Pediatr. 8:7.es
dc.identifier.urihttps://doi.org/10.3389/fped.2020.00007es
dc.identifier.urihttp://hdl.handle.net/11447/4932
dc.language.isoenes
dc.subjectNeonatal respiratory carees
dc.subjectMeta-analysises
dc.subjectSystematic reviewses
dc.subjectClinical decision-makinges
dc.subjectInfant-newbornes
dc.titleSystematic Reviews in Neonatal Respiratory Care: Are Some Conclusions Misleading?es
dc.typeArticlees

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