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Omalizumab treatment on severe asthma patients: Pediatric experience in Chile and literature review

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dc.contributor.author Herrera, Ana Maria
dc.contributor.author Hernandez, Jury
dc.contributor.author Perillan, Jose
dc.contributor.author Lezana, Viviana
dc.contributor.author Alvarez, Cecilia
dc.contributor.author Marinovic, Maria
dc.contributor.author Navarrete, Pamela
dc.contributor.author Cruz, Carolina
dc.contributor.author Campusano, Luis
dc.date.accessioned 2017-12-29T16:02:49Z
dc.date.available 2017-12-29T16:02:49Z
dc.date.issued 2016
dc.identifier.citation Rev Chil Enferm Respir 2016; 32: 160-168
dc.identifier.uri http://hdl.handle.net/11447/1828
dc.identifier.uri http://dx.doi.org/10.4067/S0717-73482016000300004
dc.description.abstract This paper presents clinical experience with Omalizumab treatment in 8 pediatric patients in Chile. All children presented difficult to control asthma despite receiving high intensity treatment, with low quality of life. All patients were studied in order to discard errors in asthma diagnosis and to evaluate asthma treatment adherence and inhalation technique. After evaluation, patients proven to have severe therapy resistant asthma were indicated treatment with Omalizumab. Significant clinical improvement was observed, with reduced asthma symptoms and number of exacerbations, as well as an improved quality of life. Omalizumab showed a good safety profile with mild and transient adverse reactions in 6 administrations of a total of 122.
dc.format.extent 9
dc.language.iso spa
dc.publisher Sociedad Chilena de Enfermedades Respiratorias
dc.subject Omalizumab
dc.subject asthma
dc.subject anti-asthmatic agents
dc.subject antibodies
dc.subject anti-idiotypic
dc.subject child
dc.subject quality of life
dc.title Omalizumab treatment on severe asthma patients: Pediatric experience in Chile and literature review
dc.title.alternative Tratamiento del asma severo con Omalizumab: experiencia pediátrica en Chile y revisión de la literatura
dc.type Artículo


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