Publication:
Comorbidities in Chilean patients with psoriasis: a Global Health care Study on Psoriasis

Simple item page
dc.contributor.authorValenzuela, Fernando
dc.contributor.authorDe la Cruz, Claudia
dc.contributor.authorLecaros, Cristóbal
dc.contributor.authorFernández, Javier
dc.contributor.authorHevia, Gonzalo
dc.contributor.authorMaul, Lara
dc.contributor.authorThyssen, Jacob
dc.contributor.authorVera, Cristian
dc.contributor.authorEgeberg, Alexander
dc.contributor.authorArmijo, Daniela
dc.contributor.authorPizarro, Cristian
dc.contributor.authorRiveros, Tatiana
dc.contributor.authorCorrea, Hernan
dc.contributor.authorGuglielmetti, Antonio
dc.contributor.authorDidaskalu, Johannes
dc.contributor.authorWu, Jashin
dc.contributor.authorGriffiths, Christopher
dc.contributor.authorRomiti, Ricardo
dc.contributor.authorMaul, Julia
dc.date.accessioned2023-11-30T13:44:27Z
dc.date.available2023-11-30T13:44:27Z
dc.date.issued2022
dc.description.abstractBackground. Psoriasis is a chronic inflammatory skin diseaseas sociated with several important medical comorbidities.There ares cant data available onthe comorbidities of patients with psoriasis inSouthAmerica. Aim. To examine the comorbidity profile of adult patients with psoriasis inChile and its association with severity of psoriasis. Methods. Thiswasamulticentre, cross-sectional study involving16hospitalsand clinics inChile,whichuseda48-itemquestionnaire tostudyclinician-andpatientreported outcomes and comorbidities. Inferential analyses were performed by psoriasis severity, using Fisher exact test, Student t-test andmultivariable logistic regression. Results. In total, 598 adult patients with psoriasis were included (51.1%male; meanage49.2 15.1years); 48.5% mildand 51.4% moderate to severe;Psoriasis Area and Severity Index 11.6 11.5; body surface area 14.7 18.2%. Plaque psoriasiswas themost commonphenotype (90.2%), followedbyguttate (13.4%). Psoriatic arthritis occurred in27.3%of patients. Comorbidities were reported in 60.2%of all patientswith psoriasis. Frequent concomitant diseaseswere obesity (25.3%), hypertension (24.3%), Type 2 diabetes mellitus (T2DM) (18.7%), dyslipidaemia (17.4%), metabolic syndrome (16.7%) and depression (14.4%). After adjustment, significant as sociations were found between moderate to severe psoriasis andobesity,T2DM and nonalcoholic fatty liver disease (NAFLD) compared with mild psoriasis. Conclusions. Were portal arge study of comorbidities, including depression,dyslipidaemia, T2D Mand NAFLD, in people with psoriasis inChile. The prevalence of comorbidities with psoriasis in Chile appears similar to that found inWestern
dc.description.versionVersión Aceptada
dc.identifier.citationValenzuela F, De La Cruz C, Lecaros C, Fernández J, Hevia G, Maul LV, Thyssen JP, Vera-Kellet C, Egeberg A, Armijo D, Pizarro C, Riveros T, Correa H, Guglielmetti A, Didaskalu JA, Wu JJ, Griffiths CEM, Romiti R, Maul JT. Comorbidities in Chilean patients with psoriasis: a Global Healthcare Study on Psoriasis. Clin Exp Dermatol. 2022 Dec;47(12):2234-2241. doi: 10.1111/ced.15384
dc.identifier.doihttps://doi.org/10.1111/ced.15384
dc.identifier.urihttps://repositorio.udd.cl/handle/11447/8060
dc.language.isoen
dc.subjectChile / epidemiology
dc.subjectComorbidity
dc.subjectCross-Sectional Studies
dc.subjectDelivery of Health Care
dc.subjectDiabetes Mellitus, Type 2* / epidemiology
dc.subjectDyslipidemias
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectNon-alcoholic Fatty Liver Disease* / epidemiology
dc.subjectObesity / epidemiology
dc.subjectPsoriasis* / epidemiology
dc.titleComorbidities in Chilean patients with psoriasis: a Global Health care Study on Psoriasis
dc.typeArticle
dcterms.accessRightsAcceso Abierto
dcterms.sourceClinicaland Experimental Dermatology
dspace.entity.typePublication

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Comorbidities in Chilean patients with psoriasis a Global Health care Study on Psoriasis.pdf
Size:
579.96 KB
Format:
Adobe Portable Document Format
Description:
Texto Completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.63 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services