Impact of myocardial scar burden on microvascular resistance reserve in patients with coronary artery disease

Hoshino, Masahiro; Hoek, Roel; Jukema, Ruurt; Dahdal, Jorge; Van Diemen, Pepijn; Hopman, Luuk; Raijmakers, Pieter; Driessen, Roel; Twisk , Jos; Danad, Ibrahim; Kakuta, Tsunekazu; Knuuti, Juhani; Knaapen, Paul

Publication:
Impact of myocardial scar burden on microvascular resistance reserve in patients with coronary artery disease

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Impact of myocardial scar burden on microvascular resistance reserve in patients with coronary artery disease.pdf (1.5 MB)

Date

2026

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Article

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Artículos Medicina y Ciencias de la Salud

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https://doi.org/10.1007/s00259-025-07112-6

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https://hdl.handle.net/11447/11168

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Abstract

Purpose: The impact of myocardial scar on coronary microcirculation is not well understood. This study aims to evaluate the association between microvascular resistance reserve (MRR) and scar tissue. ...

Citation

Hoshino, M., Hoek, R., Jukema, R. A., Dahdal, J., van Diemen, P., Hopman, L. H. G. A., Raijmakers, P., Driessen, R., Twisk, J., Danad, I., Kakuta, T., Knuuti, J., & Knaapen, P. (2025). Impact of myocardial scar burden on microvascular resistance reserve in patients with coronary artery disease. European journal of nuclear medicine and molecular imaging, 52(9), 3312–3320. https://doi.org/10.1007/s00259-025-07112-6

Keywords

Cardiac magnetic resonance imaging , Fractional flow reserve , Late gadolinium enhancement , Microvascular resistance reserve , [15O] H2O PET

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