Publication: Amelioration of morphine withdrawal syndrome by systemic and intranasal administration of mesenchymal stem cell-derived secretome in preclinical models of morphine dependence
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Gallardo, Javiera
Quezada, Mauricio
Ponce, Carolina
Berríos, Pablo
Santapau, Daniela
De Gregorio, Cristian
Quintanilla, María
Morales, Paola
Herrera, Mario
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Background: Morphine is an opiate commonly used in the treatment of moderate to severe pain. However, prolonged administration can lead to physical dependence and strong withdrawal symptoms upon cessa...
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Quezada M, Ponce C, Berríos-Cárcamo P, Santapau D, Gallardo J, De Gregorio C, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M, Israel Y, Andrés-Herrera P, Hipólito L, Ezquer F. Amelioration of morphine withdrawal syndrome by systemic and intranasal administration of mesenchymal stem cell-derived secretome in preclinical models of morphine dependence. CNS Neurosci Ther. 2023 Nov 6. doi: 10.1111/cns.14517
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