Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia

Keller-Rosenthal, Noy; Sarig, Ofer; Malovitski, Kiril; Rubinstein, Rotem; Haitin, Yoni; Larrondo Gálvez, Jorge Felipe; Lenzy, Yolanda; Dlova, Ncoza; McMichael, Amy; Sprecher, Eli

Publication:
Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia

Files

Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates.pdf (4.87 MB)

Date

2026

Type:

Article

Collections

Artículos Medicina y Ciencias de la Salud

Descargas totales

0

Vistas totales

1

Métricas

Gestores bibliográficos

Authors

Keller-Rosenthal, Noy

Larrondo Gálvez, Jorge Felipe

item.page.doiurl

https://doi.org/10.1016/j.jid.2025.10.609

URI

https://hdl.handle.net/11447/10949

item.page.accessRights

Acceso Abierto

Abstract

Central centrifugal cicatricial alopecia (CCCA) is the most common form of primary scarring alopecia in women of African descent, typically characterized by progressive hair loss originating at the ve...

Citation

Keller-Rosenthal N, Sarig O, Giladi M, Malovitski K, Rubinstein R, Haitin Y, Larrondo J, Lenzy Y, Dlova N, McMichael A, Sprecher E. Pathogenic variants affecting peptidyl arginine deiminase 3 and its major substrates underlie central centrifugal cicatricial alopecia. J Invest Dermatol. 2026 Jun;146(6):1596-1604.e2. doi: 10.1016/j.jid.2025.10.609

Keywords

CCCA , PADI3 , S100A3 , Scarring alopecia , Trichohyalin

Estadísticas de uso

1 0,8 0,5 0,3 0