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Myocardial perfusion imaging in advanced coronary artery disease

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dc.contributor.authorHoek, Roel
dc.contributor.authorVan Diemen, Pepijn
dc.contributor.authorSomsen, Yvemarie
dc.contributor.authorDe Winter, Ruben W.
dc.contributor.authorJukema, Ruurt
dc.contributor.authorDahdal, Jorge
dc.contributor.authorRaijmakers, Pieter
dc.contributor.authorDriessen, Roel
dc.contributor.authorDanad, Ibrahim
dc.contributor.authorKnaapen, Paul
dc.date.accessioned2026-09-15T19:20:58Z
dc.date.available2026-09-15T19:20:58Z
dc.date.issued2025
dc.description.abstractMyocardial perfusion imaging (MPI) is widely adapted as a noninvasive technique to assess the presence and extent of ischemia in patients with symptoms suggestive of obstructive coronary artery disease (CAD). However, as CAD advances, several factors can complicate the interpretation of MPI, subsequently impacting clinical decision-making. This review focuses on the utility of MPI by means of cardiac magnetic resonance (CMR) imaging, single-photon emission computed tomography (SPECT) and positron emission tomography (PET) in patients with advanced CAD-the latter characterized by documented CAD (i.e. prior myocardial infarction [MI] and/or percutaneous coronary intervention [PCI]), prior coronary artery bypass grafting (CABG) or the presence of a chronic total occlusion (CTO). It will discuss factors impacting the interpretation of MPI, the diagnostic performance for detecting obstructive CAD and coronary microvascular dysfunction (CMD), as well as the role of MPI in guiding revascularization.
dc.description.versionVersión Aceptada
dc.identifier.citationHoek, R., van Diemen, P. A., Somsen, Y. B. O., de Winter, R. W., Jukema, R. A., Dahdal, J. E., Raijmakers, P. G., Driessen, R. S., Danad, I., & Knaapen, P. (2025). Myocardial perfusion imaging in advanced coronary artery disease. European journal of clinical investigation, 55(7), e70024. https://doi.org/10.1111/eci.70024
dc.identifier.doihttps://doi.org/10.1111/eci.70024
dc.identifier.urihttps://hdl.handle.net/11447/11141
dc.language.isoen
dc.subjectCardiac magnetic resonance imaging
dc.subjectChronic total occlusion
dc.subjectCoronary artery bypass grafting
dc.subjectCoronary artery disease
dc.subjectCoronary microvascular dysfunction
dc.subjectMyocardial infarction
dc.subjectMyocardial perfusion imaging
dc.subjectPercutaneous coronary intervention
dc.subjectPositron emission tomography
dc.subjectSingle‐photon emission computed tomography
dc.titleMyocardial perfusion imaging in advanced coronary artery disease
dc.typeArticle
dcterms.accessRightsAcceso Abierto
dcterms.sourceEuropean journal of clinical investigation
dspace.entity.typePublication

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