Publication: ¿Ha disminuido la colectomía por crisis de colitis ulcerosa?
| dc.contributor.author | Besser, Nicolás | |
| dc.contributor.author | Chacón, Erika | |
| dc.contributor.author | Iglesias, Andrés | |
| dc.contributor.author | Alvarez-Lobos, Manuel | |
| dc.contributor.author | Pavez, Carolina | |
| dc.contributor.author | Villalón, Constanza | |
| dc.contributor.author | Urrejola, Gonzalo | |
| dc.contributor.author | Zuñiga, Alvaro | |
| dc.contributor.author | Molina, María Elena | |
| dc.contributor.author | Miguieles, Rodrigo | |
| dc.contributor.author | Bellolio, Felipe | |
| dc.date.accessioned | 2024-05-28T18:06:22Z | |
| dc.date.available | 2024-05-28T18:06:22Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | Background: Treatment for moderate-severe active ulcerative colitis (UC) includes steroids, biologic therapy and total colectomy. Aim: To describe the features of patients with moderate to severe active UC, their hospital evolution and need for colectomy. Material and Methods: Non-concurrent cohort study of all patients admitted to our institution with a diagnosis of moderate or severe UC crisis between January 2008 and May 2019. Truelove Witts (TW) criteria were used to categorize disease severity. Twelve-month colectomy-free survival was estimated with Kaplan-Meier survival analysis. Results: One hundred-twenty patients aged 16 to 89 (median 35) years had 160 admissions for acute moderate to severe UC. Median admission per patient was 1 (1-3), and median hospital stay was six days (1-49). Cytomegalovirus and Clostridioides difficile were found in 17.5 and 14.2% of crises, respectively. Corticosteroids were used in all crises and biologic therapy in 6.9% of them. Emergency or elective colectomies were performed in 18.3 and 6.7% of patients, respectively. The need for emergency total colectomy decreased from 24.6 to 7.8% (Risk ratio 3.16, p < 0.01) between de first and second half of the study period. Kaplan-Meier analysis for long term colectomy-free survival in both periods confirmed this decrease (p < 0.01). Conclusions: Medical treatment for moderate to severe UC crises had a 86.3% success and a small percentage required emergency total colectomy. Emergency surgery decreased in the last decade. | |
| dc.description.version | Versión publicada | |
| dc.format.extent | 8 p. | |
| dc.identifier.citation | Besser Nicolás, Chacón Erika, Iglesias Andrés, Álvarez-Lobos Manuel, Pavez Carolina, Villalón Constanza et al . ¿Ha disminuido la colectomía por crisis de colitis ulcerosa?. Rev. méd. Chile [Internet]. 2023 Mar [citado 2024 Mayo 28] ; 151( 3 ): 313-320. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872023000300313&lng=es. http://dx.doi.org/10.4067/s0034-98872023000300313. | |
| dc.identifier.doi | http://dx.doi.org/10.4067/s0034-98872023000300313 | |
| dc.identifier.uri | https://hdl.handle.net/11447/8904 | |
| dc.language.iso | es | |
| dc.subject | Colectomy | |
| dc.subject | Colitis | |
| dc.subject | Ulcerative | |
| dc.subject | Inflammatory Bowel Diseases | |
| dc.title | ¿Ha disminuido la colectomía por crisis de colitis ulcerosa? | |
| dc.title.alternative | Has colectomy for moderate-severe active ulcerative colitis decreased? | |
| dc.type | Article | |
| dcterms.accessRights | Acceso abierto | |
| dcterms.source | Revista Médica de Chile | |
| dspace.entity.type | Publication |