Publication:
T1b gallbladder cancer: is extended resection warranted?

Simple item page
dc.contributor.authorChavez, Montserrat
dc.contributor.authorDe Aretxabala, Xabier
dc.contributor.authorLosada, Hector
dc.contributor.authorPortillo, Norberto
dc.contributor.authorCastillo, Felipe
dc.contributor.authorBustos, Luis
dc.contributor.authorRoa, Ivan
dc.date.accessioned2026-09-11T15:19:17Z
dc.date.available2026-09-11T15:19:17Z
dc.date.issued2025
dc.description.abstractBackground: Although the prognosis for gallbladder cancer (GBCA) improves with early diagnosis and aggressive surgical treatment, the management of patients with muscle layer invasion (T1b) remains controversial. This study aimed to analyze the optimal surgical approach for these patients. Methods: A database was queried for patients with early T1b GBCA treated at four Chilean hospitals. Patients were prospectively treated and registered by the same surgical team at each hospital. Clinical outcomes, including survival rates according to the type of surgery, were analyzed. Results: Between 1988 and 2023, 129 Chilean patients were pathologically diagnosed with T1b GBCA. Simple cholecystectomy (SC) was performed in 86 patients (66.7 %), while extended cholecystectomy (EC) was performed in 43 patients. The overall 5-year survival rate was 83 %, with no significant difference between SC and EC patients. Conclusion: Simple cholecystectomy demonstrated survival rates comparable to extended cholecystectomy for patients with T1b GBCA. More extensive resections did not improve the prognosis.
dc.description.versionVersión Aceptada
dc.identifier.citationChavez M, de Aretxabala X, Losada H, Portillo N, Castillo F, Bustos L, Roa I. T1b gallbladder cancer: is extended resection warranted? HPB (Oxford). 2025 Apr;27(4):523-529. doi: 10.1016/j.hpb.2024.12.018
dc.identifier.doihttps://doi.org/10.1016/j.hpb.2024.12.018
dc.identifier.urihttps://hdl.handle.net/11447/11120
dc.language.isoen
dc.subjectGallbladder Neoplasms / pathology
dc.titleT1b gallbladder cancer: is extended resection warranted?
dc.typeArticle
dcterms.accessRightsAcceso Abierto
dcterms.sourceHPB : the official journal of the International Hepato Pancreato Biliary Association
dspace.entity.typePublication

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
T1b gallbladder cancer is extended resection warranted.pdf
Size:
449.43 KB
Format:
Adobe Portable Document Format
Description:
Texto Completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
347 B
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services