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Biomarkers for dementia in Latin American countries: Gaps andopportunities

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dc.contributor.authorParra, Mario A.
dc.contributor.authorOrellana, Paulina
dc.contributor.authorLeón, Tomas
dc.contributor.authorVictoria, Cabello G.
dc.contributor.authorHenriquez, Fernando
dc.contributor.authorGomez, Rodrigo
dc.contributor.authorAvalos, Constanza
dc.contributor.authorDamian, Andres
dc.contributor.authorSlachevsky Chonchol, Andrea
dc.contributor.authorIbañez, Agustin
dc.contributor.authorZetterberg, Henrik
dc.contributor.authorTijms, Betty M.
dc.contributor.authorYokoyama, Jennifer S.
dc.contributor.authorPiña-Escudero, Stefanie D.
dc.contributor.authorCochran, Nicholas
dc.contributor.authorMatallana, Diana L.
dc.contributor.authorAcosta, Daisy
dc.contributor.authorAllegri, Ricardo
dc.contributor.authorArias-Suáres, Bianca P.
dc.contributor.authorBarra, Bernardo
dc.contributor.authorBehrens, María Isabel
dc.contributor.authorBrucki, Sonia M.D.
dc.contributor.authorBusatto, Geraldo
dc.contributor.authorCaramelli, Paulo
dc.contributor.authorCastro-Suarez, Sheila
dc.contributor.authorContreras, Valeria
dc.contributor.authorCustodio, Nilton
dc.contributor.authorDansilio, Sergio
dc.contributor.authorDe la Cruz-Puebla, Myriam
dc.contributor.authorCruz de Souza, Leonado
dc.contributor.authorDíaz, Monica M.
dc.contributor.authorDuque, Lissette
dc.contributor.authorFarias, Gonzalo A.
dc.contributor.authorFerreira, Sergio T.
dc.contributor.authorMagrath Guimet, Nahuel
dc.contributor.authorKmaid, Ana
dc.contributor.authorLira, David
dc.contributor.authorLopera, Francisco
dc.contributor.authorMar Meza, Beatriz
dc.contributor.authorMiotto, Eliane C.
dc.date.accessioned2024-06-03T18:05:40Z
dc.date.available2024-06-03T18:05:40Z
dc.date.issued2023
dc.descriptionRicardo Nitrini, Alberto Nuñez, Santiago O'Neill, John Ochoa, Maritza Pintado-Caipa, Elisa de Paula França Resende, Shannon Risacher, Luz Angela Rojas, Valentina Sabaj, Lucas Schilling, Allis F Sellek, Ana Sosa, Leonel T Takada, Antonio L Teixeira, Martha Unaucho-Pilalumbo, Claudia Duran-Aniotz
dc.description.abstractLimited knowledge on dementia biomarkers in Latin American and Caribbean (LAC)countries remains a serious barrier. Here, we reported a survey to explore the ongo-ing work, needs, interests, potential barriers, and opportunities for future studiesrelated to biomarkers. The results show that neuroimaging is the most used biomarker(73%), followed by genetic studies (40%), peripheral fluids biomarkers (31%), and cere-brospinal fluid biomarkers (29%). Regarding barriers in LAC, lack of funding appears toundermine the implementation of biomarkers in clinical or research settings, followedby insufficient infrastructure and training. The survey revealed that despite the abovebarriers, the region holds a great potential to advance dementia biomarkers research.Considering the unique contributions that LAC could make to this growing field,we highlight the urgent need to expand biomarker research. These insights allowedus to propose an action plan that addresses the recommendations for a biomarkerframework recently proposed by regional experts.
dc.description.versionVersión aceptada
dc.format.extent15 p.
dc.identifier.citationParra MA, Orellana P, Leon T, Victoria CG, Henriquez F, Gomez R, Avalos C, Damian A, Slachevsky A, Ibañez A, Zetterberg H, Tijms BM, Yokoyama JS, Piña-Escudero SD, Cochran JN, Matallana DL, Acosta D, Allegri R, Arias-Suárez BP, Barra B, Behrens MI, Brucki SMD, Busatto G, Caramelli P, Castro-Suarez S, Contreras V, Custodio N, Dansilio S, la Cruz-Puebla M, de Souza LC, Diaz MM, Duque L, Farías GA, Ferreira ST, Guimet NM, Kmaid A, Lira D, Lopera F, Meza BM, Miotto EC, Nitrini R, Nuñez A, O'Neill S, Ochoa J, Pintado-Caipa M, Resende EPF, Risacher S, Rojas LA, Sabaj V, Schilling L, Sellek AF, Sosa A, Takada LT, Teixeira AL, Unaucho-Pilalumbo M, Duran-Aniotz C. Biomarkers for dementia in Latin American countries: Gaps and opportunities. Alzheimers Dement. 2023 Feb;19(2):721-735. doi: 10.1002/alz.12757.
dc.identifier.doihttps://doi.org/ 10.1002/alz.12757
dc.identifier.urihttps://hdl.handle.net/11447/8998
dc.language.isoen
dc.rightsAtribución-NoComercial-CompartirIgual 3.0 Chile (CC BY-NC-SA 3.0 CL)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/cl/
dc.subjectDementia
dc.subjectDiagnosis
dc.subjectHumans
dc.subjectLatin America
dc.titleBiomarkers for dementia in Latin American countries: Gaps andopportunities
dc.typeArticle
dcterms.accessRightsAcceso abierto
dcterms.sourceAlzheimer’s and Dementia
dspace.entity.typePublication
relation.isAuthorOfPublicatione25c3d3e-63b5-4e04-951a-12a4989aa772
relation.isAuthorOfPublication.latestForDiscoverye25c3d3e-63b5-4e04-951a-12a4989aa772

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