Publication:
From cadaveric donation to cryopreserved total skin allografts: Transforming the Chilean skin donation model

Simple item page
dc.contributor.authorFonseca, Marcelo
dc.contributor.authorCañete, Aldo
dc.contributor.authorMandriaza, Luana
dc.contributor.authorGómez, Jennifer
dc.contributor.authorMasiá, Jaume
dc.contributor.authorMarcelain, Katherine
dc.contributor.authorIbaceta, Dino
dc.contributor.authorErazo, Cristian
dc.contributor.authorGámez, Brenda
dc.contributor.authorSoto, Carolina
dc.contributor.authorValdés, Cristóbal
dc.date.accessioned2026-09-14T14:26:33Z
dc.date.available2026-09-14T14:26:33Z
dc.date.issued2025
dc.description.abstractBackground: The clinical utility of skin allografts (SA) is well established. However, the donation and procurement of cadaveric skin-historically the primary source of SA-remain limited in many countries. A skin donation model based on the use of excess surgical tissue from body contouring procedures was introduced and compared with the traditional cadaveric donation model. Methods: A retrospective review of skin donations in Chile was conducted over two periods (2017-2019 and 2022-2024), analyzing the performance and characteristics of two donation pathways: cadaveric and living donors. Results: During the first period (2017-2019), four cadaveric donors provided a total of 10,959 cm² of skin. In the second period (2022-2024), 353 donors contributed 153,585 cm² of skin, of which 348 were living donors (131,997 cm²) and five were cadaveric (21,588 cm²). Conclusions: Initially conceived as a complementary strategy, the living donor model has evolved to become the primary source of skin allografts in Chile. This approach significantly increases the availability of SA, broadens therapeutic indications, and promotes the concept of transforming excess surgical tissue into valuable therapeutic resources. Moreover, it enables the production of cryopreserved full-thickness skin allografts (CTSA), which serve not only as temporary wound coverage but also as dermal regenerative scaffolds, particularly beneficial in the treatment of burns affecting functionally and aesthetically critical areas. This new paradigm supports a more accessible and sustainable culture of skin donation while offering promising benefits for regenerative burn care.
dc.description.versionVersión Publicada
dc.identifier.citationFonseca, M., Cañete, A., Mandriaza, L., Gómez, J., Masiá, J., Marcelain, K., Ibaceta, D., Erazo, C., Gámez, B., Soto, C., & Valdés, C. (2025). From cadaveric donation to cryopreserved total skin allografts: Transforming the Chilean skin donation model. Burns : journal of the International Society for Burn Injuries, 51(6), 107563. https://doi.org/10.1016/j.burns.2025.107563
dc.identifier.doihttps://doi.org/10.1016/j.burns.2025.107563
dc.identifier.urihttps://hdl.handle.net/11447/11124
dc.language.isoen
dc.subjectAllografts
dc.subjectSkin
dc.subjectSkin banks
dc.subjectSkin transplantation
dc.subjectTissue donors
dc.titleFrom cadaveric donation to cryopreserved total skin allografts: Transforming the Chilean skin donation model
dc.typeArticle
dcterms.accessRightsAcceso Abierto
dcterms.sourceBurns : journal of the International Society for Burn Injuries
dspace.entity.typePublication

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
From cadaveric donation to cryopreserved total skin allografts Transforming the Chilean skin donation model.pdf
Size:
3.31 MB
Format:
Adobe Portable Document Format
Description:
Texto Completo
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
347 B
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Artículos Medicina y Ciencias de la Salud

Implementado por OpenGeek Services