White matter hyperintensities and their impact in brain structure and function in alzheimer's disease and behavioral variant frontotemporal dementia across Latin America and the United States: a cross-sectional study

Altschuler, Florencia; Canziani, Verónica; Fraile, Matías; Gonzalez, Raul; Hernández, Hernán; Baez, Sandra; Migeot, Joaquín; Fittipaldi, Sol; Maito, Marcelo; Legaz, Agustina; Godoy, Maria; Moguilner, Sebastián; Cruzat, Josephine; Coronel, Carlos; Tagliazucchi, Enzo; Santamaria, Hernando; Reyes, Pablo; Matallana, Diana; Avila, José; Slachevsky Chonchol, Andrea; Behrens, María; Custodio, Nilton; Cardona, Juan; Brusco, Luis; Bruno, Martin; Sosa, Ana; Pina, Stefanie; Takada, Leonel; Franca, Elisa de Paula; Possin, Katherine; De Oliveira, Maira; Hu, Kun; Lawlor, Brian; Yokoyama, Jennifer; Miller, Bruce; Lopera, Francisco; Martin, Adolfo; Medel, Vicente; Ibañez, Agustin; Gonzalez, Cecilia

Publication:
White matter hyperintensities and their impact in brain structure and function in alzheimer's disease and behavioral variant frontotemporal dementia across Latin America and the United States: a cross-sectional study

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White matter hyperintensities and their.pdf (2.16 MB)

Date

2025

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Article

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Artículos Medicina y Ciencias de la Salud

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Authors

Altschuler, Florencia

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https://doi.org/10.1186/s13195-025-01832-5

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https://hdl.handle.net/11447/11194

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Abstract

Background: White matter hyperintensities (WMHs) are a core manifestation of normal and pathological aging and are potentially linked to geographical differences in social and physical exposomes. Prev...

Citation

Altschuler, F., Canziani, V., Fraile-Vázquez, M., Gonzalez-Gomez, R., Hernández, H., Baez, S., Migeot, J., Fittipaldi, S., Maito, M. A., Legaz, A., Godoy, M. E., Moguilner, S., Cruzat, J., Coronel-Oliveros, C., Tagliazucchi, E., Garcia, H. S., Reyes, P., Matallana, D. L., Avila-Funes, J. A., Slachevsky, A., … Campo, C. G. (2025). White matter hyperintensities and their impact in brain structure and function in alzheimer's disease and behavioral variant frontotemporal dementia across Latin America and the United States: a cross-sectional study. Alzheimer's research & therapy, 17(1), 188. https://doi.org/10.1186/s13195-025-01832-5

Keywords

Alzheimer’s disease , Frontotemporal dementia , Latin America , MRI , White Matter Hyperintensities

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