Genomic variation in Saccharomyces cerevisiae influences paraquat response through differential oxidative stress and vacuolar adaptations

Rubilar, Juan; Szenfeld, Benjamín; Cubillos, Francisco; Klein, Andrés

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Genomic variation in Saccharomyces cerevisiae influences paraquat response through differential oxidative stress and vacuolar adaptations

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Genomic variation in Saccharomyces cerevisiae influences paraquat response through differential oxidative stress and vacuolar adaptations.pdf (6.97 MB)

Date

2025

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Article

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Artículos Medicina y Ciencias de la Salud

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0

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2

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item.page.doiurl

https://doi.org/10.1016/j.ecoenv.2025.119426

URI

https://hdl.handle.net/11447/11085

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Abstract

The conserved genetics between Saccharomyces cerevisiae and mammals makes yeast an ideal model for studying the biological effects of paraquat (PQ), an herbicide linked to Parkinson's disease (PD) ris...

Citation

Rubilar JC, Szenfeld B, Cubillos FA, Klein AD. Genomic variation in Saccharomyces cerevisiae influences paraquat response through differential oxidative stress and vacuolar adaptations. Ecotoxicol Environ Saf. 2025 Nov 15;307:119426. doi: 10.1016/j.ecoenv.2025.119426

Keywords

Herbicide , Paraquat , Parkinson's disease , Pollution , Saccharomyces cerevisiae

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