Publication: Diffusion-weighted imaging as predictor of acute ischemic stroke etiology
| dc.contributor.author | brunser, alejandro | |
| dc.contributor.author | Mansilla, Eloy | |
| dc.contributor.author | NAVIA, VICTOR | |
| dc.contributor.author | Mazzon, Enrico | |
| dc.contributor.author | Rojo, Alexis | |
| dc.contributor.author | Cavada, Gabriel | |
| dc.contributor.author | Olavarría, Verónica V. | |
| dc.contributor.author | Munoz Venturelli, Paula | |
| dc.contributor.author | Lavados, Pablo | |
| dc.date.accessioned | 2023-12-06T20:24:58Z | |
| dc.date.available | 2023-12-06T20:24:58Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Background: Topographic patterns may correlate with causes of ischemic stroke. Objective: To investigate the association between diffusion weighted imaging (DWI) and Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. Methods: We included 1019 ischemic stroke patients. DWI were classified as: i) negative; ii) DWI single lesion (cortico-subcortical, cortical, subcortical ≥20 mm, or subcortical <20 mm); iii) scattered lesions in one territory (small scattered lesions or confluent with additional lesions); and iv) multiple lesions (multiple unilateral anterior circulation [MAC], multiple posterior circulation [MPC], multiple bilateral anterior circulation [MBAC], and multiple anterior and posterior circulations [MAP]). Results: There was a relationship between DWI patterns and TOAST classification (p<0.001). Large artery atherosclerosis was associated with small, scattered lesions in one vascular territory (Odds Ratio [OR] 4.22, 95% confidence interval [95%CI] 2.61–6.8), MPC (OR 3.52; 95%CI 1.54–8.03), and subcortical lesions <20 mm (OR 3.47; 95%CI 1.76–6.85). Cardioembolic strokes correlated with MAP (OR 4.3; 95%CI 1.64–11.2), cortico-subcortical lesions (OR 3.24; 95%CI 1.9–5.5) and negative DWI (OR 2.46; 95%CI 1.1–5.49). Cryptogenic strokes correlated with negative DWI (OR 4.1; 95%CI 1,84–8.69), cortical strokes (OR 3.3; 95%CI 1.25–8.8), MAP (OR 3.33; 95%CI 1.25–8.81) and subcortical lesion ≥20 mm (OR 2.44; 95%CI 1,04–5.73). Lacunar strokes correlated with subcortical lesions diameter <20 mm (OR 42.9; 95%CI 22.7–81.1) and negative DWI (OR 8.87; 95%CI 4.03–19.5). Finally, MBAC (OR 9.25; 95%CI 1.12–76.2), MAP (OR 5.54; 95%CI 1.94–15.1), and MPC (OR 3.61; 95%CI 1.5–8.7) correlated with stroke of other etiologies. Conclusions: A relationship exists between DWI and stroke subtype | |
| dc.description.version | Versión publicada | |
| dc.format.extent | 7 p. | |
| dc.identifier.citation | Brunser AM, Mansilla E, Navia V, Mazzon E, Rojo A, Cavada G, Olavarría V, Venturelli PM, Lavados PM. Diffusion-weighted imaging as predictor of acute ischemic stroke etiology. Arq Neuropsiquiatr. 2022 Apr;80(4):353-359. doi: 10.1590/0004-282X-ANP-2021-0080. | |
| dc.identifier.doi | https://doi.org/10.1590/0004-282X-ANP-2021-0080 | |
| dc.identifier.uri | https://repositorio.udd.cl/handle/11447/8149 | |
| dc.language.iso | en | |
| dc.subject | Stroke | |
| dc.subject | Ischemic stroke | |
| dc.subject | Diffusion magnetic resonance imaging | |
| dc.subject | Diagnosis | |
| dc.title | Diffusion-weighted imaging as predictor of acute ischemic stroke etiology | |
| dc.title.alternative | Imágenes por difusión cerebral como predictor de la etiología del accidente cerebrovascular isquémico agudo | |
| dc.type | Article | |
| dcterms.accessRights | Acceso abierto | |
| dcterms.source | Arquivos de Neuro-Psiquiatria | |
| dspace.entity.type | Publication | |
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