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Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research

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dc.contributor.authorNuytemans, Karen
dc.contributor.authorFranzen, Sanne
dc.contributor.authorBroce, Iris J.
dc.contributor.authorCaramelli, Paulo
dc.contributor.authorEllajosyula, Ratnavalli
dc.contributor.authorFinger, Elizabeth
dc.contributor.authorGupta, Veer
dc.contributor.authorGupta, Vivek
dc.contributor.authorIllán-Gala, Ignacio
dc.contributor.authorLoi, Samantha M.
dc.contributor.authorMorhardt, Darby
dc.contributor.authorPijnenburg, Yolande
dc.contributor.authorRascovsky, Katya
dc.contributor.authorWilliams, Monique M.
dc.contributor.authorYokoyama, Jennifer S.
dc.contributor.authorAcosta-Uribe, Juliana
dc.contributor.authorAkinyemi, Rufus
dc.contributor.authorAlladi, Suvarna
dc.contributor.authorAyele, Biniyam A.
dc.contributor.authorAyhan, Yavuz
dc.contributor.authorBourdage, Renelle
dc.contributor.authorCastro-Suarez, Sheila
dc.contributor.authorCruz de Souza, Leonardo
dc.contributor.authorDacks, Penny
dc.contributor.authorBoer, Sterre C. M. de
dc.contributor.authorLeon, Jessica de
dc.contributor.authorDodge, Shana
dc.contributor.authorGrasso, Stephanie
dc.contributor.authorGhoshal, Nupur
dc.contributor.authorKamath, Vidyulata
dc.contributor.authorKumfor, Fiona
dc.contributor.authorMatias-Guiu, Jordi A.
dc.contributor.authorNarme, Pauline
dc.contributor.authorNielsen, T. Rune
dc.contributor.authorOkhuevbie, Daniel
dc.contributor.authorPiña-Escudero, Stefanie
dc.contributor.authorRuiz-Garcia, Ramiro
dc.contributor.authorRyan, Brigid
dc.contributor.authorScarioni, Marta
dc.contributor.authorSlachevsky Chonchol, Andrea
dc.contributor.authorSuarez-Gonzalez, Aida
dc.contributor.authorLead Tee, Boon
dc.contributor.authorTsoy , Elena
dc.contributor.authorUlugut, Hulya
dc.contributor.authorChiadi U Onyike, Chiadi U.
dc.contributor.authorBabulal, Ganesh M.
dc.contributor.authorISTAART Frontotemporal Dementia and Related Disorders PIA
dc.contributor.authorISTAART Diversity and Disparities PIA
dc.date.accessioned2025-01-21T16:03:35Z
dc.date.available2025-01-21T16:03:35Z
dc.date.issued2024
dc.description.abstractFrontotemporal dementia (FTD) is one of the leading causes of young-onset dementia before age 65, typically manifesting as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). Although FTD affects all populations across the globe, knowledge regarding the pathophysiology and genetics derives primarily from studies conducted in North America and Western Europe. Globally, biomedical research for FTD is hindered by variable access to diagnosis, discussed in this group's earlier article, and by reduced access to expertise, funding, and infrastructure. This perspective paper was produced by two professional interest areas of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) and discusses the field's current status on the cross-cultural aspects of basic and translational research in FTD (including that focused on epidemiology, genetics, biomarkers, and treatment). It subsequently provides a summary of gaps and needs to address the disparities and advance global FTD biomedical research.
dc.description.versionVersión publicada
dc.format.extent23 p.
dc.identifier.citationNuytemans K, Franzen S, Broce IJ, Caramelli P, Ellajosyula R, Finger E, Gupta V, Gupta V, Illán-Gala I, Loi SM, Morhardt D, Pijnenburg Y, Rascovsky K, Williams MM, Yokoyama JS, Acosta-Uribe J, Akinyemi R, Alladi S, Ayele BA, Ayhan Y, Bourdage R, Castro-Suarez S, de Souza LC, Dacks P, de Boer SCM, de Leon J, Dodge S, Grasso S, Ghoshal N, Kamath V, Kumfor F, Matias-Guiu JA, Narme P, Nielsen TR, Okhuevbie D, Piña-Escudero S, Ruiz-Garcia R, Ryan B, Scarioni M, Slachevsky A, Suarez-Gonzalez A, Tee BL, Tsoy E, Ulugut H, Onyike CU, Babulal GM; ISTAART Frontotemporal Dementia and Related Disorders PIA, ISTAART Diversity and Disparities PIA. Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research. Alzheimers Dement. 2024 Dec;20(12):9014-9036. doi: 10.1002/alz.14312.
dc.identifier.doihttps://doi.org/10.1002/alz.14312
dc.identifier.urihttps://hdl.handle.net/11447/9687
dc.language.isoen
dc.subjectBiomarkers
dc.subjectCultural diversity
dc.subjectEpidemiology
dc.subjectEthnicity
dc.subjectFrontotemporal dementia
dc.subjectGenetics
dc.subjectInfrastructure
dc.titleGaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research
dc.typeArticle
dcterms.accessRightsAcceso abierto
dcterms.sourceAlzheimer’s Dementia
dspace.entity.typePublication
relation.isAuthorOfPublicatione25c3d3e-63b5-4e04-951a-12a4989aa772
relation.isAuthorOfPublication.latestForDiscoverye25c3d3e-63b5-4e04-951a-12a4989aa772

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