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Longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance

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Abstract

Treatment resistance affects up to one in four individuals with psychosis in the first few years of illness. However, there is limited information about the brain changes associated with treatment res...

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Tepper, A., Vásquez, J., Díaz Dellarossa, C., Ramirez-Mahaluf, J. P., Aguirre, J., Barbagelata, D., Aceituno, D., Undurraga, J., Nachar, R., Mena, C., McCutcheon, R. A., McGuire, P., Gonzalez-Valderrama, A., & Crossley, N. A. (2025). Longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance. Schizophrenia (Heidelberg, Germany), 11(1), 114. https://doi.org/10.1038/s41537-025-00653-7

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