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Morphine self-administration is inhibited by the antioxidant N‐acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration

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Authors

Quintanilla, María Elena
Morales, Paola
Santapau, Daniela
Gallardo, Javiera
Rebolledo, Rocío
Riveras, Gabriel
Acuña, Tirso
Herrera-Marschitz, Mario
Israel, Yedy

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22 p.

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Abstract

Background The treatment of opioid addiction mainly involves the medical administration of methadone or other opioids, aimed at gradually reducing dependence and, consequently, the need for illicit op...

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Citation

Quintanilla ME, Morales P, Santapau D, Gallardo J, Rebolledo R, Riveras G, Acuña T, Herrera-Marschitz M, Israel Y, Ezquer F. Morphine self-administration is inhibited by the antioxidant N-acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration. PLoS One. 2024 Oct 29;19(10):e0312828. doi: 10.1371/journal.pone.0312828.

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