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Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity

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dc.contributor.authorQuiroz, Yakeel
dc.contributor.authorAguillón, David
dc.contributor.authorArboleda, Joseph
dc.contributor.authorBocanegra, Yamile
dc.contributor.authorCardona, Gloria
dc.contributor.authorCorrada, Maria
dc.contributor.authorDiez, Ibai
dc.contributor.authorGarcia, Elkin
dc.contributor.authorKosik, Kenneth
dc.contributor.authorMartinez, Lusiana
dc.contributor.authorPineda, David
dc.contributor.authorPosada, Rafael
dc.contributor.authorRoman, Norbel
dc.contributor.authorSepulveda, Diego
dc.contributor.authorSlachevsky Chonchol, Andrea
dc.contributor.authorSoto, Marcio
dc.contributor.authorTabilo, Evelyn
dc.contributor.authorVasquez, Daniel
dc.contributor.authorVillegas, Andrés
dc.date.accessioned2026-09-25T17:11:25Z
dc.date.available2026-09-25T17:11:25Z
dc.date.issued2025
dc.description.abstractIntroduction: Global life expectancy has steadily increased in recent decades, resulting in a significant rise in the number of individuals aged 80 years and older. This trend is also evident in Latin America, where life expectancy is improving, though at varying rates across countries and regions. Methods: Partnering with the Neurosciences Group of Antioquia (GNA), we launched a Colombian study on resilience in families with autosomal dominant Alzheimer's disease and the oldest-old population. Over the past 2 years, the project has expanded to include participants from Peru, Chile, and Costa Rica. Results: This research led to the first symposium on Brain Resilience and Healthy Longevity, held in Medellín, Colombia, in August 2024. Discussion: The article summarizes key discussions from the symposium, highlighting the most promising opportunities for brain resilience and prevention research in the region and offering recommendations for future research to promote healthy aging and dementia-free communities. Highlights: Uncovering the genetic and physiological drivers of cognitive resilience, neurodegeneration resistance, and healthy longevity is essential for maintaining brain function as we age. "Superagers" and cognitively resilient individuals from Latin American families with Alzheimer's disease offer valuable insights into brain protection mechanisms. Studying the interplay of socio-environmental and genetic factors in the oldest-old is key to understanding healthy longevity and improving dementia prevention. The inaugural Brain Resilience and Healthy Longevity Symposium highlights the need for global collaboration to uncover factors that drive cognitive resilience and healthy aging in Latin America, advancing dementia prevention.
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dc.identifier.citationQuiroz, Y. T., Aguillón, D., Arboleda-Velasquez, J., Bocanegra, Y., Cardona-Gómez, G. P., Corrada, M. M., Diez, I., Garcia-Cifuentes, E., Kosik, K., Martinez, L., Pineda-Salazar, D., Posada, R., Roman, N., Sepulveda-Falla, D., Slachevsky, A., Soto-Añari, M., Tabilo, E., Vasquez, D., & Villegas-Lanau, A. (2025). Driving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity. Alzheimer's & dementia : the journal of the Alzheimer's Association, 21(3), e70037. https://doi.org/10.1002/alz.70037
dc.identifier.doihttps://doi.org/10.1002/alz.70037
dc.identifier.urihttps://hdl.handle.net/11447/11187
dc.language.isoen
dc.subjectAlzheimer's resistance
dc.subjectLatin America
dc.subjectbrain resilience
dc.subjecthealthy aging
dc.subjectoldest‐old
dc.titleDriving research on successful aging and neuroprotection in Latin America: Insights from the inaugural symposium on brain resilience and healthy longevity
dc.typeArticle
dcterms.accessRightsAcceso Abierto
dcterms.sourceAlzheimer's & dementia : the journal of the Alzheimer's Association
dspace.entity.typePublication
relation.isAuthorOfPublicatione25c3d3e-63b5-4e04-951a-12a4989aa772
relation.isAuthorOfPublication.latestForDiscoverye25c3d3e-63b5-4e04-951a-12a4989aa772

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