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Inbreeding and Gallbladder Cancer Risk: HomozygosityAssociations Adjusted for Indigenous American Ancestry, BMI,and Genetic Risk of Gallstone Disease

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Abstract

Latin Americans have a rich genetic make-up that translates into heterogeneous fractions of the autosomal genome in runs of homozygosity (FROH) and heterogeneous types and proportions of indigenous Am...

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Ceballos F, Boekstegers F, Scherer D, Barahona Ponce C, Marcelain K, Gárate-Calderón V, Waldenberger M, Morales E, Rojas A, Munoz C, Retamales J, de Toro G, Vera Kortmann A, Barajas O, Rivera MT, Cortés A, Loader D, Saavedra J, Gutiérrez L, Ortega A, Bertrán ME, Bartolotti L, Gabler F, Campos M, Alvarado J, Moisán F, Spencer L, Nervi B, Carvajal-Hausdorf D, Losada H, Almau M, Fernández P, Olloquequi J, Salinas P, Lorenzo Bermejo J. Inbreeding and Gallbladder Cancer Risk: Homozygosity Associations Adjusted for Indigenous American Ancestry, BMI, and Genetic Risk of Gallstone Disease. Cancers (Basel). 2024 Dec 17;16(24):4195. doi: 10.3390/cancers16244195. PMID: 39766094

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