Person: Sacomori, Cinara
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Sacomori
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Cinara
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Publication Propiedades psicomĆ©tricas de la versiĆ³n chilena del cuestionario de calidad de vida para mieloma mĆŗltiple(2024) Lorca, Luz Alejandra; Sacomori, Cinara; PeƱa, Camila; Barrera, Claudia; Salazar, Melissa; LeĆ£o, Ivana; Valladares, Ximena; Rojas, ChristineObjetivos: Evaluar consistencia interna y validez de constructo del QLQ-MY20 para valoraciĆ³n de calidad de vida en sobrevivientes de mieloma mĆŗltiple en Chile. MĆ©todos: Estudio transversal, realizado entre marzo 2020 y diciembre 2022. Participaron 118 personas de dos hospitales pĆŗblicos. Se utilizaron los cuestionarios QLQ-C30 y QLQ-MY20. Fueron evaluadas la consistencia interna con alfa de Cronbach (Ī±) y validez de constructo mediante pruebas de hipĆ³tesis (Mann Whitney y correlaciĆ³n de Spearman). Resultados: El promedio de edad de los participantes era 67,2 (DE=9,2) aƱos. Consistencia interna para escala completa (Ī±=0,779), dimensiĆ³n āsĆntomas de la enfermedadā (Ī±=0,671), dimensiĆ³n āefectos secundarios de los tratamientosā (Ī±=0,538) y dimensiĆ³n āperspectiva de futuroā (Ī±=0,670). Se comprobaron cuatro de las cinco hipĆ³tesis de la validez de constructo: presentaron mĆ”s sĆntomas las mujeres, personas con peor performance estatus, con dolor y con peor fatiga. Conclusiones: La versiĆ³n chilena del QLQ-MY20 presenta adecuada consistencia interna y validez de constructo.Publication ValidaciĆ³n del cuestionario EORTC QLQ -CR29 para evaluaciĆ³n de la calidad de vida relacionada a la salud de personas adultas con cĆ”ncer colorrectal en Chile(2024) Lorca Parraguez, Luz Alejandra; Sacomori, Cinara; Pizarro, Marta; Leao Ribeiro, Ivana; Vidal, Rodrigo; Rebolledo, GonzaloIntroducciĆ³n: Personas con cĆ”ncer colorrectal (CCR) pueden presentar efectos adversos, perjudicando la calidad de vida relacionada a la salud (CVRS). Objetivo: Validar el mĆ³dulo QLQ CR2-9 para evaluaciĆ³n de la CVRS, en Chile. Materiales y mĆ©todo: Estudio transversal que incluyĆ³ 170 personas con CCR. Se analizaron la consistencia interna y validez de constructo del instrumento con test de hipĆ³tesis. Resultados: 117 personas (68,8%) fueron evaluadas antes de la cirugĆa y 53 (31,2%) despuĆ©s de la cirugĆa. La consistencia interna del QLQ CR-29 fue Ī±=0,838. Fueron comprobadas las hipĆ³tesis planteadas: Los pacientes evaluados antes de la cirugĆa se quejaron mĆ”s de āsangre/mucosidad en las hecesā, ādolor abdominalā, āpĆ©rdida de cabelloā e āhinchazĆ³n abdominalā, mientras que los pacientes evaluados despuĆ©s presentaron mĆ”s āincontinencia fecalā (p<0,05). Antes de la cirugĆa, los pacientes con CCR presentaron mayores valores de āfrecuencia urinariaā, āfrecuencia de deposicionesā, ādolor en las nalgasā, āproblemas con el gustoā y āvergĆ¼enzaā; mientras que aquellos con cĆ”ncer de colon que se quejaban mĆ”s de āsangre/mucosidad en las hecesā (p<0,05). DespuĆ©s de la cirugĆa, los pacientes con cĆ”ncer de recto tenĆan mayor āfrecuencia de deposicionesā, āeliminaciĆ³n de gasesā y āvergĆ¼enzaā (p=0,004) en comparaciĆ³n con los con cĆ”ncer de colon (p<0,05). Los pacientes ostomizados presentaron mĆ”s āincontinencia fecalā y āvergĆ¼enzaā (p<0,001). Fueron observadas correlaciones positivas y negativas bajas entre la mayorĆa de las dimensiones del QLQ C-29 con las dimensiones del QLQ C-30. ConclusiĆ³n: La versiĆ³n chilena del mĆ³dulo QLQ CR-29 es adecuada para evaluar la CVRS en personas con CCR.Publication Photobiomodulation therapy to prevent oral mucositis and functional impairment in adult patients with haematological cancer undergoing haematopoietic stem cell transplantation: randomised trial protocol(2024) LĆ³pez-Espinoza, Tomas; Sacomori, Cinara; Araya- Castro, Paulina; Quintiliano Scarpelli Dourado, Daiana; RoldĆ”n, Paola; PeƱa- Espinoza, MĆ³nica; Ferreira de Rezende, Laura; LĆ³pez- Vidal, HernĆ”nIntroduction Oral mucositis is a highly prevalent condition in individuals treated for haematological neoplasms, primarily during haematopoietic stem cell transplantation (HSCT). The condition is known to delay recovery processes, increasing the risk of infection, the number of interventions and the length of hospital stays. The proposed Photobiomodulation Therapy for Oral Mucositis and Functional Impairment Transplantation Trial aims to assess the effectiveness and acceptability of using photobiomodulation in the oral cavity to prevent oral mucositis and functional impairment in adult patients undergoing HSCT. Methods and analysis This is an assessor- blinded and statistician- blinded, parallel- group randomised controlled clinical trial (photobiomodulation vs control group). Participants and setting: 30 patients, aged 18ā65 years, with haematological neoplasms undergoing HSCT at the ClĆnica DĆ”vila Oncology and Bone Marrow Transplant Unit. Primary outcome measures: oral mucositis will be assessed daily using the WHO grading scale, beginning on the day of transplant through day 20 post- transplant. Researchers will assess functional capacity using a 2 min step test, handgrip strength with the Jamar digital dynamometer, lower limb strength using a 30ā sit- to- stand test and quality of life with the Functional Assessment of Cancer Therapy- Bone Marrow Transplantation Questionnaire. Acceptability will be assessed by logging treatment adherence and using a Visual Analogue Scale. Assessments will occur at two time points (1): on admission to the transplant unit, before starting the conditioning regimen and (2) on the day of discharge. Intervention: three times per week photobiomodulation therapy using a diode laser device will begin the first day of conditioning and continue through day 3 post-transplant. Ethics and dissemination The ClĆnica DĆ”vila and Universidad del Desarrollo Clinical Research Ethics Committees approved this study in accordance with the Helsinki Declaration. Patientsā informed consent will be required. The dissemination strategy includes publication in scientific journals as well as presentations in the media and at conferences.Publication Spanish version of the ICIQ-Bowel questionnaire among colorectal cancer patients: construct and criterion validity: Comprehensive assessment of bowel function(2023) Sacomori, Cinara; Lorca, Luz Alejandra; MartĆnez-Mardones, MĆ³nica; Pizarro-Hinojosa, Marta Natalia; Rebolledo-DĆaz, Gonzalo SebastiĆ”n; Vivallos-GonzĆ”lez, Jessica AndreaPurpose: Bowel complaints are very common among patients with colorectal cancer. However, the most used questionnaires for colorectal cancer survivors do not comprehensively comprise bowel symptoms. This study aimed to examine construct and criterion validity, as well as internal consistency, of the Chilean Version of the International Consultation on Incontinence Questionnaire Bowel Module (ICIQ-B) among people with colorectal cancer. Methods: Cross-sectional, validation study performed with 106 colorectal cancer patients from Hospital del Salvador, Chile. Bowel function was assessed with the ICIQ-B. Construct validity was assessed with confirmatory factor analysis and hypothesis testing. Specific items of a quality-of-life questionnaire (EORTC QLQ-CR29) were used to correlate with similar ICIQ-B items for criterion validity. For internal consistency, Cronbach's alpha was computed. Results: For construct validity, the confirmatory factor analysis showed that the three factors model did not fit our data. Meanwhile, hypothesis testing favored the construct validity of the instrument, considering that rectal cancer patients showed worse bowel pattern (p = 0.001), bowel control (p = 0.001) and quality of life (p < 0.001) scores compared to colon cancer patients. In addition, those patients assessed before surgery also presented worse scores bowel control (p = 0.023) and quality of life (p = 0.009) compared to post-surgical patients. Regarding criterion validity, the ICIQ-B items showed a significant correlation with similar QLQ-CR29 items. The internal reliability of the instrument was good (Cronbach's Ī± = 0.909). Conclusion: Considering that this questionnaire appraises bowel function in more depth, it is recommended for use in clinical practice and research with colorectal cancer patients.