Browsing by Author "Schmidt, Carlos"
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Item Effects of socioeconomic status in cognition of people with schizophrenia: results from a Latin American collaboration network with 1175 subjects(2021) Sanguinetti, Letícia; Alliende, Luz Maria; Castañeda, Carmen Paz; Castro, Mariana; Guinjoan, Salvador; Massuda, Raffael; Berberian, Arthur; Fonseca, Ana; Gadelha, Ary; Bressan, Rodrigo; Crivelaro, Marisa; Louzã, Mario; Undurraga, Juan; González, Alfonso; Nacha, Rubén; Nieto, Rodrigo; Montes, Cristian; Silva, Hernán; Langer, Álvaro; Schmidt, Carlos; Mayol, Rocío; Díaz, Ana; Valencia, Johanna; López, Carlos; Solís, Rodolfo; Reyes, Francisco; De la Fuente, Camilo; Crossley, Nicolás; Gama, ClarissaBackground. Cognition heavily relies on social determinants and genetic background. Latin America comprises approximately 8% of the global population and faces unique challenges, many derived from specific demographic and socioeconomic variables, such as violence and inequality. While such factors have been described to influence mental health outcomes, no large-scale studies with Latin American population have been carried out. Therefore, we aim to describe the cognitive performance of a representative sample of Latin American individuals with schizophrenia and its relationship to clinical factors. Additionally, we aim to investigate how socioeconomic status (SES) relates to cognitive performance in patients and controls. Methods. We included 1175 participants from five Latin American countries (Argentina, Brazil, Chile, Colombia, and Mexico): 864 individuals with schizophrenia and 311 unaffected subjects. All participants were part of projects that included cognitive evaluation with MATRICS Consensus Cognitive Battery and clinical assessments. Results. Patients showed worse cognitive performance than controls across all domains. Age and diagnosis were independent predictors, indicating similar trajectories of cognitive aging for both patients and controls. The SES factors of education, parental education, and income were more related to cognition in patients than in controls. Cognition was also influenced by symptomatology. Conclusions. Patients did not show evidence of accelerated cognitive aging; however, they were most impacted by a lower SES suggestive of deprived environment than controls. These findings highlight the vulnerability of cognitive capacity in individuals with psychosis in face of demographic and socioeconomic factors in low- and middle-income countries.Item Meditation focused on self-observation of the body impairs metacognitive efficiency(2019) Schmidt, Carlos; Reyes, Gabriel; Barrientos, Mauricio; Langer, Álvaro I.; Sackur, JérômeIn the last decade of research on metacognition, the literature has been focused on understanding its mechanism, function and scope; however, little is known about whether metacognitive capacity can be trained. The specificity of the potential training procedure is in particular still largely unknown. In this study, we evaluate whether metacognition is trainable through generic meditation training, and if so, which component of meditation would be instrumental in this improvement. To this end, we evaluated participants’ metacognitive efficiency before and after two types of meditation training protocols: the first focused on mental cues (Mental Monitoring [MM] training), whereas the second focused on body cues (Self-observation of the Body [SoB] training). Results indicated that while metacognitive efficiency was stable in MM training group, it was significantly reduced in the SoB group after training. This suggests that metacognition should not be conceived as a stable capacity but rather as a malleable skill.