Browsing by Author "Ronco, Ricardo"

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    La formación versus el conocimiento
    (Facultad de Medicina, Clínica Alemana Universidad del Desarrollo, 2020) Ronco, Ricardo
    Al momento de escribir este comentario nos encontramos en el segundo semestre de este año 2020, asomándonos al mes de la Patria. Ha sido un tiempo extrañamente inasible, con el sello de poco control sobre lo que pasa y la gran incertidumbre que esto arrastra. Especialmente en este contexto constituye un motivo de orgullo y reconocimiento la publicación de este segundo número de la Revista Confluencia. En esta oportunidad se muestran 32 trabajos de 7 de las 9 carreras de la Facultad. A través de tres conceptos, quiero destacar nuestro rol de formadores versus simples transmisores de conocimiento: Descubrimiento, Reflexión e Interdisciplina.
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    Mild hypothermia attenuates lung edema and plasma interleukin-1 beta in a rat mechanical ventilation-induced lung injury model
    (2011) Cruces, Pablo; Ronco, Ricardo; Erranz, Benjamín; Conget, Paulette; Carvajal, Cristóbal; Donoso, Alejandro; Díaz, Franco
    Recent data suggest that deep hypothermia has protective effects on experimental induced lung injury. It is not well known if these effects persist with mild hypothermia. The authors hypothesized that mild hypothermia may attenuate lung injury and decrease local and systemic proinflammatory cytokines in a rat model of injurious mechanical ventilation (MV). Twelve Sprague-Dawley male adult rats were anesthetized, intubated, and randomly allocated to normothermia group (37 degrees C) (NT) or mild hypothermia group (34 degrees C) (MH). After 2 hours of deleterious MV (peak inspiratory pressure [PIP] 40 cm H2O, zero end-expiratory pressure [ZEEP], and inspiratory fraction of oxygen [Fio(2)] 100%), arterial blood gases, lung gravimetry, and histological study were obtained. Protein content, interleukin (IL)-1 beta, and tumor necrosis factor (TNF)-alpha were measured in plasma and bronchoalveolar lavage (BAL) fluid. Subjects that underwent MH had a significant lower wet-to-dry lung weight ratio (8.32 +/- 0.28 vs. 10.8 +/- 0.49, P = .01), IL-1 beta plasma concentration (0.6 +/- 0.6 vs. 10.27 +/- 2.80 pg/mL, P = .0048) and Paco(2). There were no differences in terms of Pao(2), histological injury, or BAL protein content. In this model of injurious mechanical ventilation, subjects treated with mild hypothermia had less lung edema and lower plasma IL-1 beta. Some of known beneficial effects of deep hypothermia can be obtained with mild hypothermia.
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    Revista Confluencia Volumen 5, número 2, 2022 (Edición completa)
    (2022) Facultad de Medicina, Clínica Alemana de Santiago - Universidad del Desarrollo; Ronco, Ricardo; Jadue, Liliana; Pérez, Claudia; López, María Angélica; Molina, Jorge; Castillo, Marcela; Ratner, Rinat; Mayol, Mimy; Ocaranza, Danilo; Parra, María Adriana; Villarroel, Vivian; Fuentes, Daniela; Lizana, Marcelo

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