Browsing by Author "Morales Murillo, Luis"
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Publication Reactivation of adult-onset Still's disease after use of the COVID-19 ChAdOx1-S vaccine(2022) Ibáñez, Sebastián; Morales Murillo, Luis; Rivera Vergara, Matías de la; Saldías Martínez, RobertoA woman in her 60s with a history of adult-onset Still's disease (AOSD) in remission for 14 years received the ChAdOx1-S vaccine as a booster to her initial vaccination schedule (two doses of CoronaVac vaccine 6 months apart). Two weeks later, she consulted for symptoms suggestive of AOSD reactivation. This was confirmed during hospitalisation, where renal and cardiac involvement were also observed. Despite using high-dose corticosteroids, troponin T and N-terminal pro hormone B-type natriuretic peptide (NT-proBNP) were persistently elevated. Tocilizumab was used, with which the patient achieved complete remission of her symptoms and normalised her laboratory tests.