Browsing by Author "Massardo, Loreto"

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    First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR)
    (2018) Pons-Estel, Bernardo; Bonfa, Eloisa; Soriano, Enrique R.; Izcovich, Ariel; Popoff, Federico; Criniti, Juan M.; Vásquez, Gloria; Massardo, Loreto; Duarte, Margarita; Barile-Fabris, Leonor A.; García, Mercedes A.; Amigo, Mary-Carmen; Espada, Graciela; Catoggio, Luis J.; Sato, Emilia Inoue; Levy, Roger A.; Acevedo Vásquez, Eduardo M.; Chacón-Díaz, Rosa; Galarza-Maldonado, Claudio M.; Iglesias Gamarra, Antonio J.; Molina, José Fernando; Neira, Oscar; Silva, Clovis A.; Vargas Peña, Andrea; Gómez-Puerta, José A.; Scolnik, Marina; Pons-Estel, Guillermo J.; Ugolini-Lopes, Michelle R.; Savio, Verónica; Drenkard, Cristina; Alvarellos, Alejandro J.; Ugarte-Gil, Manuel F.; Babini, Alejandra; Cavalcanti, André; Cardoso Linhares, Fernanda Athayde; Haye Salinas, Maria Jezabel; Fuentes-Silva, Yurilis J.; Montandon de Oliveira E Silva, Ana Carolina; Eraso Garnica, Ruth M.; Herrera Uribe, Sebastián; Gómez-Martín, Diana; Robaina Sevrini, Ricardo; Quintana, Rosana M.; Gordon, Sergio; Fragoso-Loyo, Hilda; Rosario, Violeta; Saurit, Verónica; Appenzeller, Simone; Torres Dos Reis Neto, Edgard; Cieza, Jorge
    Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice guidelines for Latin American patients with lupus. Two independent teams rheumatologists with experience in lupus management and methodologists) had an initial meeting in Panama City, Panama, in April 2016. They selected a list of questions for the clinical problems most commonly seen in Latin American patients with SLE. These were addressed with the best available evidence and summarised in a standardised format following the Grading of Recommendations Assessment, Development and Evaluation approach. All preliminary findings were discussed in a second face-to-face meeting in Washington, DC, in November 2016. As a result, nine organ/system sections are presented with the main findings; an 'overarching' treatment approach was added. Special emphasis was made on regional implementation issues. Best pharmacologic options were examined for musculoskeletal, mucocutaneous, kidney, cardiac, pulmonary, neuropsychiatric, haematological manifestations and the antiphospholipid syndrome. The roles of main therapeutic options (ie, glucocorticoids, antimalarials, immunosuppressant agents, therapeutic plasma exchange, belimumab, rituximab, abatacept, low-dose aspirin and anticoagulants) were summarised in each section. In all cases, benefits and harms, certainty of the evidence, values and preferences, feasibility, acceptability and equity issues were considered to produce a recommendation with special focus on ethnic and socioeconomic aspects. Guidelines for Latin American patients with lupus have been developed and could be used in similar settings.
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    Recomendaciones sobre el manejo del compromiso renal del lupus eritematoso sistémico. Documento de Consenso de las Sociedades Chilenas de Nefrología y Reumatología
    (Sociedad Medica de Santiago, 2015) Aguirre, Verónica; Alvo, Miriam; Ardiles, Leopoldo; Carpio, Daniel; Foster, Carolina; Goecke, Annelise; Jalil, Roberto; Massardo, Loreto; Palma, Sergio; Roessler, Emilio; Wurgaft, Andrés
    Renal involvement affects over one half of patients with Systemic Lupus Erythematosus increasing their mortality and morbidity, including chronic renal disease and the need of renal replacement therapies. Aiming to achieve a consensus in the most relevant topics on diagnosis, therapy and follow-up of patients with lupus renal disease, the Chilean Societies of Nephrology and Rheumatology constituted a workgroup that, based on a critical review of the available literature and their experience, raised and answered by consensus a set of relevant questions. This document includes aspects related to the clinical diagnosis, the importance of a suitable histological classification, therapeutic alternatives to induce and maintain disease remission, strategies for follow-up, additional therapies and gynecological-obstetric issues.

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