Browsing by Author "Lutgring, Joseph"
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Item Multi-country cross-sectional study of colonization with multidrug-resistant organisms: protocol and methods for the Antibiotic Resistance in Communities and Hospitals (ARCH) studies(2021) Sharma, Aditya; Luvsansharav, Ulzii-Orishikh; Paul, Prabasaj; Lutgring, Joseph; Call, Douglas; Omulo, Sylvia; Laserson, Kayla; Araos, Rafael; Munita, José; Verani, Jennifer; Chowdhury, Fahmida; Mah-E Muneer, Syeda; Espinosa-Bode, Andrés; Ramay, Brooke; Cordon, Celia; Kumar, Girish; Bhatnagar, Tarun; Gupta, Neil; Park, Benjamín; Smith, Rachel M.Background: Antimicrobial resistance is a global health emergency. Persons colonized with multidrug-resistant organisms (MDROs) are at risk for developing subsequent multidrug-resistant infections, as colonization represents an important precursor to invasive infection. Despite reports documenting the worldwide dissemination of MDROs, fundamental questions remain regarding the burden of resistance, metrics to measure prevalence, and determinants of spread. We describe a multi-site colonization survey protocol that aims to quantify the populationbased prevalence and associated risk factors for colonization with high-threat MDROs among community dwelling participants and patients admitted to hospitals within a defined population-catchment area.