Browsing by Author "Jalilie, Alfredo"
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Item Complicaciones asociadas a la broncoscopía flexible: análisis de registro post- procedimiento(Sociedad Médica de Santiago, 2014) Fernández-Bussy, Sebastián; Labarca, Gonzalo; Zagolin, Mónica; Oyonarte, Maite; Isamit, Dionis; Jalilie, Alfredo; Guerra, Carlos; Chernilo, SaraBackground: Flexible bronchoscopy is a useful diagnostic tool with a relative low rate of complications. Aim: To analyze post procedure risk of complications after flexible bronchoscopy with transbronchial or bronchial biopsy. Material and Methods: The electronic database of a bronchoscopy unit at a general Hospital was analyzed. All procedures performed between 2009 and 2011 were reviewed and complications recorded. The primary outcome measure was the risk for complications defined as the percentage of procedures complicated by hemorrhage, pneumothorax, desaturation < 80% and other complications. We used a logistic regression model to explore the association between each procedure characteristic and complication. Results: One thousand seventy nine procedures were included in the analysis. Eight percent had complications. Among these, the frequency of hemorrhage was 5.9% and pneumothorax was 0.3%. Factors associated with complications were exclusive use of topical anesthesia with an odds ratio (OR) of 1.72 (confidence intervals (CI): 1.04-2.86), regular or bad intolerance to the procedure with an OR 4.70 (CI: 3.00-7.38) and performing biopsies of the upper lobes with an OR of 1.76 (CI: 1.04-2.97). Conclusions: Exclusive use of topical anesthesia, performing biopsies of the upper lobes and procedure tolerance were risk factors associated with complications following bronchoscopic biopsies.Publication Consenso de recomendaciones para tamizaje del cáncer pulmonar en Chile(2024) Suárez, Francisco; Saavedra, María; Roberti, Javier; Boyeras, Iris; Seijo, Mariana; Rodríguez, Ana; Silva, Claudio; Verdugo, Jaime; Sánchez, Felipe; Solé, Claudio; Valenzuela, Rubén; Jalilie, Alfredo; García, EzequielAim: This initiative aimed to develop recommendations for lung cancer screening in Chile through an expert consensus process. Methods: A mixed approach was used in this study. A literature review was conducted to identify recommendations. A group of 18 Chilean experts was selected to form the Delphi panel. The RAND/UCLA method and evidence-based decision-making criteria were used to guide the evaluation process. Three rounds of voting and one synchronous meeting were conducted. Results: Following a literature review and expert evaluation, 25 recommendations relevant to lung cancer screening in Chile were selected. These recommendations cover the selection of the target population, the frequency and duration of the program, and the implementation and characteristics of the programs and the health institutions that would host them. Discussion: Experts expressed concerns about the feasibility and acceptability of implementing screening programs in the local context, noting possible barriers, such as lack of awareness and costs. Local evidence needs to be generated to address the regional particularities and ensure the feasibility and effectiveness of lung cancer screening programs in Chile. Objetivo: El objetivo de este estudio es desarrollar recomendaciones para el tamizaje del cáncer pulmonar (CP) en Chile mediante un proceso de consenso de expertos. Método: Se implementó un enfoque mixto. Se realizó una revisión de literatura para identificar posibles recomendaciones y luego se seleccionó un grupo de 18 expertos chilenos que conformaron un panel Delphi. Se utilizó el método RAND/UCLA y los criterios de Evidencia a Decisión para guiar el proceso de evaluación. Se realizaron tres rondas de votación y una reunión sincrónica. Resultados: Tras la revisión de la literatura y la evaluación por parte de expertos, se seleccionan 25 recomendaciones pertinentes para el tamizaje de CP en Chile. Estas recomendaciones abarcan la selección de la población objetivo, la frecuencia y duración del programa, la implementación y características de los programas y las instituciones de salud que los albergarían. Discusión: Los expertos expresan preocupaciones sobre la factibilidad y aceptabilidad de implementar programas de tamizaje en el contexto local, señalando posibles barreras como la falta de concientización y los costos. Es necesario generar evidencia local para abordar las particularidades regionales y garantizar la viabilidad y eficacia de los programas de tamizaje de CP en Chile.Item Rendimiento diagnóstico de la broncoscopia con biopsia transbronquial en el estudio de lesiones sugerentes de cáncer pulmonar(Sociedad Médica de Santiago, 2015) Fernández-Bussy, Sebastián; Labarca, Gonzalo; Canals, Sofía; Zagollín, Mónica; Oyonarte, Maite; Isamit, Dionis; Jalilie, Alfredo; Guerra, Carlos; Chernilo, SaraBackground: Bronchoscopy is a minimally invasive procedure used for the diagnosis of lung cancer. Aim: To report our experience with bronchoscopy and transbronchial biopsies for the diagnosis of potentially malignant pulmonary lesions. Material and Methods: Revision of electronic records from patients who underwent transbronchial biopsies seeking for lung cancer. The diagnostic yield of the procedure was evaluated using pathology reports or a 24 months follow up. Results: 261 patients were included. Bronchoscopy was diagnostic in 65% of cases. Lesions mean diameter was 51 mm (range 9-120 mm). Diagnostic yield for lesions less than 30 mm was 59%, for lesions less than 35 mm was 61%, and for lesions over 40 mm was 69%. The presence of malignant lesions and their location in the superior or middle lobe were associated with a better predictive value of the procedure. TNM staging was IIIB/IV in 80% of the patient at the time of diagnosis. Conclusions: The diagnostic yield of bronchoscopy is influenced by the etiology and location of lung lesions.