Browsing by Author "Gosch, Marianne"
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Item Do not forget to check the scalp in systemic light-chain amyloidosis(2021) Larrondo, Jorge; Gosch, Marianne; Pena, Camila; Cabrera, Raúl; Jeraldo, Cecilia; Castro, Alex; McMichael, AmySystemic light chain amyloidosis (AL) is a nonproliferative plasma cell disorder in which fragments of immunoglobulin deposit in tissues. Clinical manifestations are often nonspecific, making diagnosis challenging.Biopsy of involved organs is the gold standard to confirm the diagnosis; however, internal organ biopsy may beunsafe because of a significant risk of bleeding.1 New techniques to improve diagnosis are needed.Publication Lupus Miliaris Disseminatus Faciei(2022) Gosch, Marianne; Larrondo, JorgeA woman in her 40s presented with a year history of an asymptomatic, expanding papular eruption on the face. She denied any systemic symptoms. Physical examination revealed multiple small, symmetrical, reddish brown papules on her cheeks, nose, and eyelids (Figure). Skin biopsy results showed multiple perifollicular epithelioid cell granulomas, with central areas of necrosis. Staining for fungi and acid-fast bacilli yielded negative results. A computed tomography scan of the chest, complete blood cell count, and metabolic panel were normal. A diagnosis of Lupus miliaris disseminatus faciei (LMDF) was made. The patient was refractory to treatment with systemic corticosteroids, doxycycline, and oral isotretinoin. Eight months of treatment with oral dapsone (100 mg/day) produced substantial clinical improvement that was maintained at 6-month and 1-year follow-up visitsItem Trichobacteriosis axillaris caused by Dermabacter hominis(John Wiley & Sons, 2017) Larrondo, Jorge; Porte, Lorena; Gosch, Marianne; Cabrera, Raul; Weitzel, ThomasTrichobacteriosis is a frequent superficial bacterial infection of the hair, mainly affecting sweat gland bearing areas such as axillae and genital region, and also rarely the scalp.(1-3) The disease is characterized by bacterial overgrowth forming nodular concretions, usually of yellow color (infrequently black or reddish), which are firmly attached to the hair shaft.(1,4) Clinical hallmarks are rancid, acidic odor, unpleasant "dirty" sensation, and staining of clothes. Although most cases have been associated to different species of corynebacteria, the full etiologic spectrum of this infection is uncertain .(1,5) Here we report the first case of trichobacteriosis caused by Dermabacter hominis.