Browsing by Author "Flanagan, Emma"

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    Does culture shape our understanding of others' thoughts and emotions? An investigation across 12 countries
    (2022) Quesque, François; Coutrot, Antoine; Cox, Sharon; Cruz de Souza, Leonardo; Baez, Sandra; Cardona, Juan; Mulet, Hannah; Flanagan, Emma; Neely, Alejandra; Clarens, María; Cassimiro, Luciana; Musa, Gada; Kemp, Jennifer; Botzung, Anne; Philippi, Nathalie; Cosseddu, Maura; Trujillo, Catalina; Grisales, Johan; Fittipaldi, Sol; Magrath, Nahuel; Calandri, Ismael; Crivelli, Lucia; Sedeno, Lucas; Sedeno, Lucas; Garcia, Adolfo; Moreno, Fermin; Indakoetxea, Begoña; Benussi, Alberto; Brandão, Millena; Santamaria, Hernando; Matallana, Diana; Pryanishnikova, Galina; Morozova, Anna; Iakovleva, Olga; Veryugina, Nadezda; Levin, Oleg; Zhao, Lina; Liang, Junhua; Duning, Thomas; Lebouvier, Thibaud; Pasquier, Florence; Huepe, David; Barandiaran, Myriam; Johnen, Andreas; Lyashenko, Elena; Allegri, Ricardo; Borroni, Barbara; Blanc, Frederic; Wang, Fen; Sanches, Monica; Lillo, Patricia; Teixeira, Antonio; Caramelli, Paulo; Hudon, Carol; Andrea Slachevsky; Ibáñez, Agustin; Hornberger, Michael; Bertoux, Maxime
    Measures of social cognition have now become central in neuropsychology, being essential for early and differential diagnoses, follow-up, and rehabilitation in a wide range of conditions. With the scientific world becoming increasingly interconnected, international neuropsychological and medical collaborations are burgeoning to tackle the global challenges that are mental health conditions. These initiatives commonly merge data across a diversity of populations and countries, while ignoring their specificity. Objective: In this context, we aimed to estimate the influence of participants' nationality on social cognition evaluation. This issue is of particular importance as most cognitive tasks are developed in highly specific contexts, not representative of that encountered by the world's population. Method: Through a large international study across 18 sites, neuropsychologists assessed core aspects of social cognition in 587 participants from 12 countries using traditional and widely used tasks. Results: Age, gender, and education were found to impact measures of mentalizing and emotion recognition. After controlling for these factors, differences between countries accounted for more than 20% of the variance on both measures. Importantly, it was possible to isolate participants' nationality from potential translation issues, which classically constitute a major limitation. Conclusions: Overall, these findings highlight the need for important methodological shifts to better represent social cognition in both fundamental research and clinical practice, especially within emerging international networks and consortia. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
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    Neuroanatomical Comparison of the "Word" and "Picture" Versions of the Free and Cued Selective Reminding Test in Alzheimer's Disease
    (2018) Slachevsky, Andrea; Barraza, Paulo; Hornberger, Michael; Muñoz, Carlos; Flanagan, Emma; Henríquez, Fernando; Bravo, Eduardo; Farías, Mauricio; Delgado, Carolina
    Episodic memory tests with cued recall, such as the Free and Cued Selective Reminding Test (FCSRT), allow for the delineation of hippocampal and prefrontal atrophy contributions to memory performance in Alzheimer’s disease (AD). Both Word and Picture versions of the test exist but show different profiles, with the Picture version usually scoring higher across different cohorts. One possible explanation for this divergent performance between the different modality versions of the test might be that they rely on different sets of neural correlates. The current study explores this by contrasting the neural correlates of the Word and Picture versions of the FCSRT with voxel-based morphometry (VBM) in AD and healthy subjects. We predicted that the Picture version would be associated with different cortical regions than the Word version, which might be more hippocampal-centric. When comparing 35 AD patients and 34 controls, AD patients exhibited impairments on both versions of the FCSRT and both groups performed higher in the Picture version. A region of interest analysis based on prior work revealed significant correlations between free recall of either version with atrophy of the temporal pole and hippocampal regions. Thus, contrary to expectations, performance on both the Word and the Picture version of the FCSRT is associated with largely overlapping networks. Free recall is associated with hippocampal volume and might be properly considered as an indicator of hippocampal structural integrity.

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