Browsing by Author "Díaz, Carolina"

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    Barreras asociadas al acceso y uso del sistema público de salud para la prevención y detección del VIH/Sida en población joven del país: Documento de recomendaciones para la toma de decisiones en salud
    (Universidad del Desarrollo.Facultad de Medicina Clínica Alemana. ICIM; ANID; UAI; Universidad de la Frontera, 2023) Obach, Alexandra; Sadler, Michelle; Carreño, Alejandra; Alarcón, Ana María; Cabieses, Báltica; Roberts, Antonia; Chandia, Sabrita; López, Olga; Marín, Matías; Díaz, Carolina; Branif, Marjorie
    El proyecto FONIS SA19I0091, titulado Barreras asociadas al acceso y uso del sistema público de salud para la prevención y detección del VIH/Sida en población joven del país, liderado por el Centro de Salud Global Intercultural (CeSGI), del Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, tuvo como propósito aportar a la solución del problema del aumento de VIH/Sida en jóvenes, a través de la identificación de barreras asociadas al acceso y uso del sistema público de salud (atención primaria) para la prevención y detección del VIH/Sida en población joven del país. Esto se enmarca en la problemática detectada tanto a nivel mundial como nacional, en relación a que la población joven es la que experimenta el mayor aumento en las tasas de VIH/Sida.
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    Covid-19 en trasplantados renales hospitalizados: análisis del registro multicéntrico durante la primera ola de la pandemia en chile
    (2024) Pefaur, Jacqueline; Toro, Luis; Badilla, Ximena; Ardiles, Leopoldo; Boltansky, Andrés; Rosatti, Pía; Tapia, Beatriz; Rocca, Ximena; Mur, Paola; Fernández, Alicia; Castillo, Alvaro; Díaz, Carolina; Elgueta, Leticia; García, Francisco; Müller, Hans; Mansilla, Rodrigo; Muñoz, Carolina; Salvatici, Marcelo; Selame, María Esperanza; Valenzuela, Marcela; Zamora, Daniela; Enciso, Giovanni; Panace, Rita; Cabrera, Sebastián; Ortíz, Ana Mireya; Mardones, Sandra; Oshiro, Carolina; Sánchez, Juan Eduardo; Lorca, Eduardo; Torres, Rubén
    Introduction: The severity of COVID-19 infection in kidney transplant patients has been well-documented. Objectives: This study aims to determine the epidemiological and clinical data and identify predictors of poor prognosis during the epidemic’s early stages. Material and methods: This is a national semi-prospective, multicenter study of subjects with functioning grafts who were infected during the first wave of the pandemic in Chile between March 1 and September 31, 2020. Results: during this period, we recorded the hospitalization of 97 adult patients throughout the entire national territory. The average age was 52.5 years, 62% men, 45% hypertensive, 11% coronary, 10% diabetic, and 5% with chronic obstructive pulmonary disease, with an average post-transplant follow-up of 7.2 years and an average previous renal function of 47.7ml/min/1.7m2 (CKD-EPI formula). Between the onset of symptoms and diagnosis, there was an average period of 4.8 days, with a predominance of cough (44%), dyspnea (42%), and fever (42%). 34% developed acute kidney injury, and 36% of them required dialysis support. The lethality was 30%, prevailing in those with multiple organ failure (80%) and those who required invasive mechanical ventilation (52%). In the multivariate analysis, the best predictors of mortality were older age (OR: 2.92) and living in a low-income commune (OR: 2.35). Conclusions: This national project of the Chilean Society of Nephrology provided valuable information for monitoring the epidemiological evolution of the pandemic. It also helped to propose priority vaccination strategies, adjust immunosuppressive therapy, and design logistical aspects to reduce the risks for transplant patients.

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